Quartz crystal microbalance based histidine sensor

dc.contributor.authorSönmezler, Merve
dc.contributor.authorÖzgür, Erdoğan
dc.contributor.authorYavuz, Handan
dc.contributor.authorDenizli, Adil
dc.date.accessioned2019-07-04T10:15:01Z
dc.date.available2019-07-04T10:15:01Z
dc.date.issued2019
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.descriptionYavuz, Handan ( Aksaray, Yazar )
dc.description.abstractHerein, quartz crystal microbalance (QCM) biosensor is prepared for the detection of L-histidine by attachment of L-histidine imprinted poly(EGDMA-MAH/Cu(II)) nanoparticles on QCM electrode. The imprinted nanoparticles with the size of 86.43 nm were synthesized via miniemulsion polymerization reaction. Prepared QCM sensors were characterized with ellipsometer, contact angle measurements and FTIR. The thickness measurements demonstrated that the particle thin films were almost monolayer. L-histidine solutions with a concentration range between 6.44 lM and 225.6 lM were introduced to QCM system to determine the adsorption kinetics. Selectivity of the L-histidine imprinted nanoparticles were examined using D-histidine and L-tryptophan as competitor molecules. L-histidine imprinted QCM biosensors was also used for RNAase, lysozyme, cytochrome-C and BSA to investigate the competitive adsorption of surface histidine exposed proteins.
dc.description.abstract...
dc.identifier.doi10.1080/21691401.2018.1548474
dc.identifier.endpage227en_US
dc.identifier.issn2169-1401
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage221en_US
dc.identifier.urihttps://dx.doi.org/10.1080/21691401.2018.1548474
dc.identifier.urihttps://hdl.handle.net/20.500.12451/1834
dc.identifier.volume47en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaylor & Francis Online
dc.relation.ispartofArtificial Cells, Nanomedicine, and Biotechnology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHistidine
dc.subjectAmino Acid Detection
dc.subjectMolecular İmprinting
dc.subjectQuartz Crystal Microbalance
dc.subjectAmino Asit
dc.subjectTayini Moleküler Baskı
dc.subjectKuvars Kristal Mikro Dengeleyici
dc.titleQuartz crystal microbalance based histidine sensor
dc.typeArticle

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