Quartz crystal microbalance based histidine sensor
Yükleniyor...
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Online
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Herein, quartz crystal microbalance (QCM) biosensor is prepared for the detection of L-histidine by attachment of L-histidine imprinted poly(EGDMA-MAH/Cu(II)) nanoparticles on QCM electrode. The imprinted nanoparticles with the size of 86.43 nm were synthesized via miniemulsion polymerization reaction. Prepared QCM sensors were characterized with ellipsometer, contact angle measurements and FTIR. The thickness measurements demonstrated that the particle thin films were almost monolayer. L-histidine solutions with a concentration range between 6.44 lM and 225.6 lM were introduced to QCM system to determine the adsorption kinetics. Selectivity of the L-histidine imprinted nanoparticles were examined using D-histidine and L-tryptophan as competitor molecules. L-histidine imprinted QCM biosensors was also used for RNAase, lysozyme, cytochrome-C and BSA to investigate the competitive adsorption of surface histidine exposed proteins.
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Açıklama
Yavuz, Handan ( Aksaray, Yazar )
Anahtar Kelimeler
Histidine, Amino Acid Detection, Molecular İmprinting, Quartz Crystal Microbalance, Amino Asit, Tayini Moleküler Baskı, Kuvars Kristal Mikro Dengeleyici
Kaynak
Artificial Cells, Nanomedicine, and Biotechnology
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
47
Sayı
1
