A novel prognostic biomarker for recurrent aphthous stomatitis: Calprotectin

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dc.authorid0000-0002-5292-5940
dc.authorid0000-0001-5773-4126
dc.contributor.authorKayabaşı, Serkan
dc.contributor.authorKuzucu, İhsan
dc.date.accessioned2019-10-18T07:41:58Z
dc.date.available2019-10-18T07:41:58Z
dc.date.issued2019
dc.departmentTıp Fakültesi
dc.description.abstractObjective. This study aims to investigate whether there is a correlation between serum calprotectin concentration and oral ulcer activity in patients with active recurrent aphthous stomatitis. Method. This prospective, cross-sectional, historical cohort study included 52 patients (26 with active lesions and 26 with inactive lesions) with recurrent aphthous stomatitis and 27 healthy volunteers. The relationship between the groups was statistically evaluated in terms of serum calprotectin level and other inflammatory parameters. Results. The median calprotectin value of the active lesion group (803 ng/ml) was significantly higher than that of the control group (55.4 ng/ml, p = 0.002). Furthermore, the median calprotectin value of the active lesion group was significantly higher than that of the inactive lesion group (72.5 ng/ml, p = 0.017). Conclusion. In patients with recurrent aphthous stomatitis and active ulcer lesions, the serum calprotectin value can be used as a reliable and robust prognostic marker for inflammation.
dc.description.abstract...
dc.identifier.doi10.1017/S0022215119001440
dc.identifier.endpage695en_US
dc.identifier.issue8en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage691en_US
dc.identifier.urihttps://dx.doi.org/10.1017/S0022215119001440
dc.identifier.urihttps://hdl.handle.net/20.500.12451/6877
dc.identifier.volume133en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge University Press
dc.relation.ispartofJournal of Lartngology and Otology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectStomatitis
dc.subjectAphthous
dc.subjectLeukocyte L1 Antigen Complex
dc.subjectInflammation
dc.titleA novel prognostic biomarker for recurrent aphthous stomatitis: Calprotectin
dc.typeArticle

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