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Evaluating the efficacy and benefits of vNOTES for ovarian cystectomy: a systematic review and meta-analysis
(Elsevier Ireland Ltd, 2025) Kaya, Cihan; Aktoz, Fatih; Güneş, Ali Can; Tercan, Can; Saçıntı, Koray Görkem; Yassa, Murat; AlAli, Hussein
This meta-analysis aims to evaluate the effectiveness and overall outcomes of vNOTES in ovarian cystectomy compared to conventional laparoscopy (CL). Study design: A systematic review and meta-analysis were conducted by searching PubMed/MEDLINE, EBSCO, Cochrane, and Embase databases for studies comparing vNOTES and laparoscopy for ovarian cystectomy. A comprehensive literature search was performed to identify relevant publications up to June 21, 2024. The search strategy utilized a combination of Medical Subject Headings (MeSH) terms and relevant keywords. Eligible studies included randomized controlled trials, cohort studies, and case-control studies, while case reports and studies lacking a direct comparison were excluded. Two independent reviewers assessed study eligibility and performed Risk of Bias evaluation. Quantitative synthesis was performed using meta-analysis techniques. The protocol was registered in the PROSPERO database (CRD42024560612). Results: Six studies reported operative times, with vNOTES showing a significantly shorter duration compared to CL (mean difference [MD]: −13.05 min, 95 % confidence interval [CI]: −19.04 to −7.07, I2 = 67 %). Five studies demonstrated that vNOTES was associated with shorter hospital stays (MD: −0.43 days, 95 % CI: −0.74 to −0.12, I2 = 90 %). Pain scores were also significantly lower in vNOTES patients (3 studies, MD: −1.25, 95 % CI: −1.49 to −1.01, I2 = 43 %). However, no significant differences were observed between the groups regarding hemoglobin drop, blood loss, or conversion rates. Conclusion: This systematic review and meta-analysis highlight the advantages of vNOTES ovarian cystectomy, including reduced operative times, faster recovery, lower postoperative pain, and shorter hospital stays. These findings support the wider adoption of vNOTES as an effective alternative to conventional laparoscopy for ovarian cystectomy, offering potential benefits for both patients and surgical efficiency.
A bibliometric analysis of academic publications about ıntoxication in the period from 1975 to 2020: a global and medical view
(Eskişehir Osmangazi Üniversitesi Rektörlüğü, 2022) Zengin, Musa; Karaca, Onur
Intoxication is still the major cause of morbidity and mortality worldwide. Despite the growing number of global studies about intoxication, comprehensive bibliometric studies are not available in the literature. This study aims to analyze scientific articles about intoxication/poisoning and to evaluate this subject matter from a holistic point of view. Studies about intoxication that were published in the years between 1975 and 2020 were downloaded from the Web of Science (WoS) database and analyzed by bibliometric methods. Spearman’s correlation coefficient was used for correlation analyses. Regression analysis was used to estimate publication trends in the coming years. A total of 32,320 publications about medical research were obtained. Of these publications, 17,508 (54%) were articles. A non-linear growth trend was observed for the number of intoxication articles that have been published in recent years. The most active three institutions were the University of California San Francisco (137), Harvard University (133), and Oxford University (96). Clinical Toxicology was the journal that has published the highest number of articles (683). The most active author was Michael Eddleston (92). The most common subject matters were carbon monoxide, suicide, overdose, organophosphates, toxicology, alcohol, pesticides, epidemiology, children, paraquat, and lead poisoning. In this comprehensive bibliometric study about intoxication, which is a subject matter studied with a growing trend in the literature, we have presented a summary of 17,508 articles. This study can be a beneficial resource for clinicians and scientists by presenting global outputs about intoxication and future prospects and novel subject matters for research
Evaluation of the effect of fasting on glaucoma patients
(Ali Cangül, 2021) Uyar, Enes; Ulaş, Fatih; Doğan, Ümit; Çelebi, Serdal
The aim of this research was to evaluate the effect of daytime Ramadan fasting and dehydration on intraocular pressure (IOP) and biometric parameters in primary open-angle glaucoma (POAG) patients.Methods: This prospective study included 30 eyes of 30 POAG patients who were fasting during Ramadan (Group 1), 40 healthy participants who were fasting (Group 2), and 40 healthy individuals who were not fasting (Group 3). The eyes were evaluated twice a day at approximately 8 am and 4 pm during Ramadan and 1 month after Ramadan.Results: IOP values at 4 pm were higher in Group 1 than Groups 2 and 3 in Ramadan (p=0.029 and 0.007, respectively). The diurnal reduction in IOP was significantly smaller during fasting in the glaucoma patients compared with Groups 2and 3 (p=0.012 and 0.007, respectively). Comparisons of biometric parameters revealed less reduction in central corneal thickness (CCT) values from 8 am to 4 pm in glaucoma patients than in Groups 2 and 3 (p<0.05 for all comparisons) during Ramadan and after Ramadan.Conclusion: POAG patients had a higher IOP at 4 pm during the fasting period than was seen following Ramadan. In addition, the diurnal reduction of IOP and CCT was smaller in patients with POAG compared with healthy subjects.
A combined fracture and mortality risk index useful fortreatment stratification in hip fragility fractures
(Bayçınar Tıbbi Yayıncılık, 2021) Sezgin, Erdem Aras; Tor, Ahmet Toygun; Markeviciute, Vetra; Sirka, Aurimas; Tarasevičius, Šarūnas; Raina, Deepak Bushan; Liu, Yang; Isaksson, Hanna; Tägil, Magnus; Lidgren, Lars
In this study, we aimed to assess the stratification abilityof the Fracture and Mortality Risk Evaluation (FAME) index forreoperation, new fragility fracture, and mortality during one-yearfollow-up. Patients and methods: Between November 2018 and July 2019,a total of 94 consecutive hip fragility fracture patients fromtwo centers (20 males, 74 females; mean age: 79.3±8.9 years;range, 57 to 100 years) were retrospectively analyzed. The patientswere classified into high, intermediate, and low fracture andmortality risk groups according to the Fracture Risk AssessmentTool (FRAX) score and Sernbo score, respectively, as well asnine combined categories according to the FAME index. Hospitalrecords were reviewed to identify re-fractures (reoperations,implant failure, new fragility fractures on any site) and mortality atone year following the FAME index classification. Results: Overall re-fracture and mortality rates were 20.2% and33%, respectively. High fracture risk category (FRAX-H) wassignificantly associated with higher re-fracture (odds ratio [OR]:2.9, 95% confidence interval [CI]: 1-8.2, p=0.037) and mortalityrates compared to others (OR: 3.7, 95% CI: 1.5-9.3, p=0.003).The patients classified within the FRAX-H category (n=35) haddifferent mortality rates according to their Sernbo classification;i.e., patients classified as low mortality risk (Sernbo-L) (n=17) hadlower mortality rates compared to others in this group (n=18) (35.3%and 66.7%, respectively), indicating a low statistical significance(OR: 0.3, 95% CI: 0.1-1.1, p=0.063). Similarly, within patientsclassified in Sernbo-L category (n=64), those classified as highfracture risk (FRAX-H) (n=17) had significantly higher re-fracturerates compared to others in this group (n=47) (35.3% and 8.5%,respectively), (OR: 5.9; 95% CI: 1.4-24.5), (p=0.017). Multivariatelogistic regression analyses adjusting for covariates (age, sex, lengthof hospital stay and BMI) yielded similar results. Conclusion: The FAME index appears to be a useful stratificationtool for allocating patients in a randomized-controlled trial foraugmentation of hip fragility fractures.
Bowel pathologies caused by the use of electrocautery knife in spinal surgery with facet denervation: the first experimental study
(Galenos Yayınevi, 2021) Karadağ, Mehmet Kürşat; Yardım, Ahmet; Alpaslan, Aslıhan; Aydın, Mehmet Dumlu
Monopolar electrocautery (MEC) or bipolar electrocautery (BEC) are surgical instruments commonly used in spinal surgery. Our study aimed to determine the bowel end pathologies induced by sacral parasympathetic network degeneration due to the use of MEC or BEC in spinal surgery. Method: Twenty male hybrid rabbits were used in the study, including 5 in the control group, 7 in the BEC group, and 8 in the MEC group. We used the thoracic vertebra 11-lumbar vertebra 2 (T11-L2) spinal laminectomy for the operation technique. After one week, the animals’ abdominal organs were examined on computerized tomography, and then the animals were sacrificed. The descending colon and Onuf’s nucleus/S4 spinal ganglia were histopathologically examined. The colonic degeneration scores were numbered as follows: Normal (0P), vasospasm (1P), endothelial injury (2P), thrombus (3P), colonic wall injury (4P), inflammation (5P), colonic mucosal degeneration (6P), Auerbach myenteric ganglion degeneration (7P), and necrosis (8P). The groups were scored according to 36 points, and the results were compared with the number of degenerated pudendal ganglion neurons. Results: The mean numbers of normal neurons/degenerated neurons were 22.610±962/5±2, 21.617±890/103±21, and 16.692±641/345±62 in the control, BEC, and MEC groups, respectively. The colonic degeneration score was <8 points in the control group, 9-30 points in the BEC group, and >31 points in the MEC group. Our results were statistically significant (p<0.05 for all). Conclusion: In this study, we have found that high-voltage electrical devices such as MEC/BEC may cause bowel pathologies due to their harmful effects on the Adamkiewicz artery/sacral parasympathetic network and should not be used in spinal surgery unless necessary.
Covid-19 pandemi sürecinde koroner anjiyografi yapılan akut miyokard enfarktüslü hastaların pandemi öncesi dönemle karşılaştırılması
(Mebas Medikal Basın Yayın San. ve Tic. Ltd. Şti, 2021) Gül, Murat; İnci, Sinan; Aktaş, Halil; Yıldırım, Oğuz
COVID‐19 pandemisinin, hastanemize başvuran ve koroner anjiyografi yapılan akut miyokard enfarktüslü hastaları nasıl etkilediğini araştırmak. Gereç ve Yöntem: Çalışmaya geriye dönük olarak 1 Nisan 2020‐31 Temmuz 2020 ile 1 Nisan 2019‐31 Temmuz 2019 tarihleri arasında Aksaray Üniversitesi Eğitim ve Araştırma Hastanesi’ne başvurmuş ve koroner anjiyografi yapılmış olan tüm akut miyokard enfarktüslü hastalar alındı. Hastalar pandemi grubu ve pandemi öncesi grup olarak ayrıldı. Hastaların başvuru şekilleri, kapı‐tel geçme zamanları, hastanede yatış süreleri ve hastane içi mortaliteleri değerlendirildi. Bulgular: Çalışmaya 503 hasta alındı. Pandemi grubunda 280, pandemi öncesi grupta 223 hasta yer aldı. Pandemi grubunda ST elevasyonlu miyokard enfarktüsü oranı (%56,1’e karşın, %43,9; p=0,007), subakut ST elevasyonlu miyokard enfarktüsü oranı (%19,1’e karşın %9,2; p=0,032), kapı‐tel geçme zamanı (56 dk’ya karşın 39 dk; p<0,001) ve başvuru troponin I değeri (244 pg/mL’ye karşın 100,7 pg/mL; p=0,021) daha yüksek saptandı. Pandemi grubunda hastaların daha kısa süre hastanede yattıkları gözlendi (2,16 güne karşın 3,14 gün; p<0,001). Hastane içi mortalite ise gruplar arasında benzer bulundu (%3,2’ye karşın, %3,6; p=0,818). Sonuç: Pandemi döneminde ST elevasyonlu miyokard enfarktüsü başvurularının arttığı, hastaların daha geç başvurduğu ve daha kısa süre hastanede yattığı gözlemlendi. Fakat hastane içi mortalite oranları benzer bulundu.
Dirofilaria repens is a rare cause of red eye: A case report
(Effect Publishing Agency ( EPA ), 2021) Bulut, Erkan; Gül, Adem; Dokur, Mehmet; Eroğlu, Fadime
Dirofilaria is usually stable in cats and circulates as microfilaria. A human being is the final host (dead-end host), which often leads to human dirofilariasis. We present a case of Dirofilaria repens infection located in the bulbar subconjunctival space of a 53-year-old male who presented to the emergency department with red-eye. Slit-lamp examination revealed a white-colored motile worm in the subconjunctival space of the left eye along with redness, mild chemosis, and conjunctival elevation. The parasite was surgically removed and remained undamaged. There was no symptomatic recurrence following parasite removal. The present case report also emphasizes the typical clinical features of Diroflaria repens. Dirofilaria repens should be considered in the differential diagnosis of a persistent red-eye disease, especially if it is associated with the presence of a mobile foreign body.
Readability levels of patient information texts regarding cataract surgery on websites
(Effect Publishing Agency ( EPA ), 2021) Keleş Şahin, Asena; Uyar, Enes
This study aimed to evaluate the contents and readability levels of the texts on cataract surgery on Turkish websites. A total of 300 websites were searched by the Google (www.google.com.tr) search engine using the keywords ‘cataract surgery’, ‘phaco’ and ‘phacoemulsification’. Readability values of the informative texts on the websites were analysed were calculated using the Atesman and Bezirci-Yılmaz formulas. Sites prepared by private hospitals or medical centres constituted group 1, individual sites of ophthalmologists constituted group 2, and sites providing general health information that did not belong to group 1 or group 2 constituted group 3. In total, health information presented in 85 websites was analysed. According to Atesman and Bezirci-Yılmaz, the mean readability values were 49.6 ± 7.5 and 12.9 ± 2.8, respectively. There was no statistically significant inter-group difference in terms of the average number of sentences, of words, of words with four or more syllables and of syllables (p = 0.579, p = 0.434, p = 0.236 and p = 0.336, respectively). The readability values of groups 1 and 3 were significantly different according to the Atesman and Bezirci- Yılmaz formulas (p = 0.025 and p = 0.023, respectively). In terms of content, groups 1 and 2 had relatively more comprehensive information. The readability level of information texts related to cataract surgery on Turkish websites is above the academic level recommended according to the education level of Turkey. In order to help patients make medical decisions using these websites, it is imperative to revise the contents of health information related to cataract according to the literacy level of Turkish people.
Approach differences of orthopedics and emergency medicine physicians in current treatment practices of acute traumatic first time anterior shoulder dislocation
(Süleyman Demirel University, 2021) Özmanevra, Ramadan; Demirkıran, Nihat Demirhan; Çapkın, Sercan; Özkula, Uğur; Işın, Yağmur; Kılıç, Ali İhsan
Objective Numerous techniques for the reduction of anterior glenohumeral joint dislocations have been described. However, there is no consensus on the best technique for reducing a dislocated glenohumeral joint. This study aimed to evaluate the approach of emergency specialists and orthopedic surgeons in the treatment of acute traumatic first-time anterior shoulder dislocation. Material and Methods Data used in this cross-sectional study were obtained through a web-based survey from the Turkish Orthopedics and Traumatology Association mail group and Emergency Medicine Physicians Association of Turkey mail group. All orthopedic surgeons and emergency medicine physicians who were registered in the database received an information mail regarding the aim of the questionnaire and a link to the online survey form (Google Forms, Alphabet Inc., Mountain View, CA). The survey consisted of 13 questions, which are shown with their corresponding answer options. The current practices regarding the management of acute traumatic first-time anterior shoulder dislocation among orthopedic surgeons and emergency medicine physicians in Turkey were evaluated. Results A total of 152 orthopedic surgeons and 151 emergency physicians participated in this survey. The most common maneuvers used by emergency physicians to reduce shoulder dislocations were the Hippocrates technique (19.2%) and Cunningham technique (19.2%), while orthopedic surgeons preferred the Hippocrates technique (23.7%) and Kocher technique (29.6%). It was found that orthopedic surgeons preferred Kocher and Milch maneuvers more for shoulder joint dislocation reduction compared to emergency physicians (p < 0.001 and p = 0.005, respectively). Both the pre- reduction and postreduction procedures showed variability between orthopedic surgeons and emergency physicians. Conclusion It would be more appropriate for the emergency physician and orthopedic surgeons to treat a patient with shoulder dislocation together as a team and beneficial to establish a national guideline for consensus.
Bladder distention due to electrocautery knife use in spine surgery: the first experimental study
(Kafkas Üniversitesi Tıp Fakültesi, 2021) Karadağ, Mehmet Kürşat; Yardım, Ahmet; Duman, Aslıhan; Aydın, Mehmet Dumlu
In our study, we aimed to examine the mechanism of ACA/ sacral parasympathetic network injury and its effects on the bladder, which have not been included in the literature before, due to the use of electrocautery knife in spinal surgery. Material and Method: Twenty hybrid rabbits were used in our study. Five of the animals were evaluated as the control (control group). Surgery was performed on 6 of them using bipolar electrocautery knife (BEC group) and 9 using monopolar electrocautery knife (MEC group). Th11-L2 spinal laminectomy was performed on animals during surgery. Animals were sacrificed after bladder tomography was taken one week later. After sacrification, the bladder and Onuf nucleus/S4 spinal ganglia were taken for histopathological examination. Bladder volume values and S4 ganglion density values were compared statistically using the Man Whitney-U test. Results: Bladder volume values were found to be 48±5 cm3in the control group. It was found to be 52±6 cm3in the BEC group and 75±9 cm3in the MEC group. S4 dorsal root ganglion densities were 8±3/mm3in the control group and 143±23/mm3in the BEC group, and It was found to be 643±75/mm3in the MEC group. The results were statistically significant. Conclusion: As a result of the findings we obtained in our study, we recommend that the high-voltage MEC/BEC electrocautery blade should not be used in spine surgery unless it is necessary due to its dangerous effects on AKA, sacral parasympathetic network, and consequently, the urogenital system.
Bir türk kohortunda dejeneratif rotator kaf yırtıklarının radiografik öngörücü faktörleri
(2021) Çapkın, Sercan; Güler, Serkan; Özmanevra, Ramadan
Kritik omuz açısı (CSA), lateral akromiyal açı (LAA) ve akromiyon indeksi (AI), rotator manşet yırtığı (RCT) olan hastalar ile sağlam rotator manşeti olan hastalar arasında ayrım yapmak için kullanılan yaygın radyolojik parametrelerdir. Bu çalışma, dejeneratif RCT'de bu parametrelerin tahmin gücünü değerlendirmeyi amaçlamaktadır. YÖNTEM ve GEREÇLER: Bu retrospektif çalışma, iki gruba ayrılan 92 hastadan alınan verileri içeriyordu: 47 dejeneratif tam kat supraspinatus tendon yırtığı olan 47 hastayı içeren RCT grubu ve yırtığı olmayan 45 kişiden oluşan bir kontrol grubu. Standartlaştırılmış gerçek ön-arka radyografilerden CSA, AI ve LAA ölçümleri bağımsız olarak iki ortopedi cerrahı tarafından türetilmiş ve analiz edilmiştir. Kesme değerlerini belirlemek için alıcı çalışma karakteristiği (ROC) analizleri yapılmıştır. BULGULAR: RCT ve kontrol gruplarındaki hastalar arasında yaş (p = 0.079), cinsiyet (p = 0.804) veya yaralanma tarafı (p = 0.552) açısından anlamlı farklılık bulunmadı. CSA, LAA ve AI değerleri için mükemmel gözlemciler arası güvenilirlik görüldü. Ortalama CSA (38.1°) ve AI (0.72) değerleri RCT grubunda kontrol grubuna göre anlamlı olarak daha yüksekti ve LAA için gruplar arasında anlamlı bir fark yoktu. ROC analizi, 37.95 ° kesme değeriyle CSA için 0.815'lik eğri altında bir alan (AUC) verdi ve CSA'nın RCT varlığının en güçlü öngörücüsü olduğu bulundu TARTIŞMA ve SONUÇ: CSA ve AI, Türk popülasyonunda dejeneratif RCT için yararlı prediktif faktörler olabilir.
The effect of the Covid-19 pandemic on the epidemiology of hip fractures
(Alanya Alaaddin Keykubat Üniversitesi, 2021) Aktı, Sefa; Cankaya, Deniz
This study aimed to compare the epidemiology of hip fractures in an elderly population in 6 months of the COVID-19 pandemic and the same 6-month period in the previous year to be able to reveal how the decrease in community activity beyond normal seasonal habits because of the pandemic had affected the incidence of fractures in the elderly patient population. Methods: A comparison was made of the data of patients who presented at our hospital with a hip fracture between 1 April 2020 and 30 September 2020, and those who presented in the same 6-month period in 2019 before the pandemic. Comparisons were made in respect of epidemiology, treatments applied, complication rates and mortality. The demographic data of the patients were examined, and those presenting during the pandemic were evaluated in respect of the presence of COVID-19 infection. Results: A total of 78 patients were treated in the defined study period in 2020 and 71 in the equivalent period in 2019 before the pandemic. No statistically significant change was found in the number of hip fractures in 2020 (p>0.05). No statistically significant difference was observed between the demographic data of the patients, the ASA scores, the treatment methods, or the mortality rates in the two periods (p>0.05 for all). Conclusions: The most significant finding of this study was that there was no decrease in the number of patients with hip fracture during the pandemic in 2020, compared to the equivalent period in 2019. The increase in pulmonary complications during the pandemic period demonstrates the need for special care conditions in elderly patients with hip fractures, which are still seen at a high rate despite the pandemic.
Total diz artroplastisi ameliyatlarında uygulanan anestezi yöntemlerinin retrospektif olarak incelenmesi
(Eskişehir Osmangazi Üniversitesi Rektörlüğü, 2021) Zengin, Musa; Doğan, Güvenç; Karaca, Onur; Gökçınar, Derya; Erdoğmuş, Alper; Aldemir, Özgür; Baydar, Mustafa
Total diz artroplastisi ameliyatı geçiren hastalarda uygulanan anestezi metodlarının perioperatif ve postoperatif etkilerinin retrospektif değerlendirilmesi üzerine Türkiye’de yapılan çalışmalar az sayıdadır. Bu çalışmada amacımız total diz protezi ameliyatı geçiren hastalarda uygulanan rejyonel anestezi tekniklerinin genel anesteziye göre daha iyi sonuçlar sağladığı hipotezini test etmektir. Ankara Numune Eğitim ve Araştırma Hastanesi Bilimsel Araştırma Değerlendirme Komisyonu onayı alındı. 01 Ocak 2012 ile 31 Aralık 2012 tarihleri arasında total diz artroplasti ameliyatı geçiren 247 hastanın tıbbi arşivleri ve anestezi kayıtları geriye dönük olarak incelendi. Hastaların preoperatif, intraoperatif ve postoperatif kayıtlar tutuldu. Çalışılan gruplar arasında cinsiyet, yaş, sigara içme durumu, ASA düzeyi, ameliyat şekli, eşlik eden hastalıklar, ortalama arteriyel kan basıncı, kan verilme durumu, komplikasyonlar, postoperatif yoğun bakım ihtiyacı, ameliyat ve taburculuk süreleri, peroperatif morbidite ve mortalite açısından istatistiksel olarak anlamlı bir fark olmadığı bulundu (p> 0.05). Çalışılan gruplar arasında verilen kan miktarı, verilen sıvı miktarı ve kalp hızı açısından istatistiksel olarak anlamlı fark vardı (p <0.05). Çalışmamızda total diz artroplastisi operasyonu geçiren 247 hastanın verileri retrospektif olarak incelendi. Benzer yaş grupları ve yandaş hastalıklara sahip hastalarda rejyonel anestezi uygulamaları ve genel anestezi uygulamaları arasında peroperatif morbidite ve mortalite açısından anlamlı bir fark olmadığını gözlemledik. Bu konuda daha kapsamlı meta analizlere ve çalışmalara ihtiyaç olduğu kanısındayız.
Current practices regarding the management of infrapatellar fat pad during total knee arthroplasty: A survey of orthopedic surgeons
(DNT Ortadoğu Yayıncılık AŞ, 2021) Çapkın, Sercan; Özmanevra, Ramadan; Demirkiran, Nihat Demirhan; Güler, Serkan
Bu çalışmanın amacı Türkiye'deki ortopedi cerrahları arasında primer total diz artroplastisi (TDA) sırasında infrapatellar yağ yastığının (IPFP) yönetimine ilişkin güncel uygulamaları değerlendirmektir. Gereç ve Yöntemler: Türkiye Ortopedi ve Travmatoloji Derneği veri tabanına kayıtlı ortopedi cerrahlarına yönelik web tabanlı bir anket Haziran 2020 ile Temmuz 2020 arasında gerçekleştirilmiştir. Anket, IPFP'nin yönetimine ilişkin mevcut uygulamalara ilişkin yedi sorudan oluşmaktadır (IPFP'nin korunması, birincil TDA sırasında kısmi rezeksiyon veya tam rezeksiyon). Bulgular: 1553 kayıtlı ortopedi uzmanından 266'sı (% 17) anketi tamamladı. Ortopedi cerrahlarının büyük çoğunluğu (% 75,2) TDA sırasında IPFP'nin yönetimi ile ilgili karar vermelerinin kanıta dayalı olmadığını iddia etti.
PFAPAsendromunda yeni öngörücü parametreler: nötrofil-lenfosit oranı ve trombosit-lenfosit oranı
(MEDİTAGEM Ltd. Şti., 2020) Kayabaşı, Serkan; Gül, Hüseyin Fatih
Bu çalışmada PFAPA sendromu tanısı konulan hastalar ile sağlıklı bireyler yeni inflamasyon belirteçlerinden olan nötrofil-lenfosit oranı (NLO) ve trombosit-lenfosit oranı (TLO) bakımından karşılaştırıldı.Gereç ve Yöntem: Çalışmaya PFAPA sendromu tanısı konulmuş 30 hasta (Pf grubu) (16 erkek, 14 kadın; ort. yaş 3,33; dağılım1-21 yıl) ile 30 sağlıklı birey (15 erkek, 15 kadın; ort. yaş 4,01 yıl; dağılım 1-23 yıl) (kontrol grubu) dahil edildi. Her iki grubun hematolojik parametreleri istatiksel olarak karşılaştırıldı. Nötrofil, lenfosit, trombosit değerleri ile NLO ve TLO oranları kullanıldı.Bulgular: Nötrofil, lenfosit ve trombosit değerleri karşılaştırıldığında Pf ve kontrol grubu arasında bir fark gözlenmedi(p>0.05). NLO oranları karşılaştırıldığında Pf grubunda (p=0,012) istatiksel olarak anlamlı yükseklik saptandı. TLO oranları karşılaştırıldığında ise istatiksel fark gözlenmedi (p=0,117).Sonuç: PFAPA sendromu tanısı genellikle klinik olarak konulmaktadır. Ancak tanısı zor konan vakalarda NLO oranı bir laboratuvar bulgusu olarak yardımcı olabilir.
Evaluation of newborn hearing screening results of Aksaray region
(Türkiye Klinikleri Yayınevi, 2019) Kayabaşı, Serkan; Gül, Fatih
To investigate the possible risk factors that may lead to hearing loss in newborns who failed the hearing screening tests. Material and Methods: In this retrospective study,546 newborns who failed the evoked otoacoustic emission (TEOAE) test or who underwent screening auditory evoked brainstem response (ABR) due to detected risk factors were included between2010 and 2018. The risk factors of 78 patients who failed the screening ABR test were documented.A total of 468 newborns who passed ABR screening test were evaluated as control group. The datawere compared statistically. Results: In the comparison of groups who failed and passed the ABRscreening test, the mean birth time was found to be significantly earlier (38.1±2.6 and 39.25±1.4weeks, respectively) (p=0.049), and the mean birth weight was found to be significantly lower (3001±628.2 and 3334.82 ±418 g, respectively) (p=0.032) in the failed group. The incidence of neonataljaundice and jaundice requiring phototherapy was higher in patients who failed the screening ABRtest, and this difference was statistically significant (p=0.043 and p=0.028, respectively). The newborns receiving intensive care treatment were also found to be statistically higher (p=0.028). Conclusion: The highest risk group for sensorineural hearing loss in newborns may be considered as theones with low birth weight, early birth time and receiving intensive care treatment.
The role of depression, stress and anxiety in patients with sudden sensorineural hearing loss: correlation with the dass-42 scale
(PLEKSUS BİLİŞİM TEKN.DANIŞ.TEMS.YAY.ORG.A.Ş., 2019) Kayabaşı, Serkan; Gül, Fatih
Our aim is to understand the mood states of the patients suffering from sudden hearing loss in terms of anxiety, stress and depression. Its role in etiology and its effect on prognosis was also investigated.Methods: The study included 100 patients (67 males, 33 females; mean age 46.5 years) who were diagnosed with sudden sensorineural hearing loss (SSHL). The DASS-42 questionnaire, which measures depression, anxiety, and stress, was filled out before the treatment of SSHL. Audiometric tests were performed to determine the pure tone average on days 1,3 and 7.Results: There was no difference between males and females according to DASS-42 mean depression, anxiety and stress scores (p = 0.785, p = 0.832, p = 0.712, respectively). While there was no statistically significant difference between the presence and absence of tinnitus in terms of depression and stress scores, a statistically significant difference was observed in terms of mean anxiety scores (p = 0.817, p = 0.134, p = 0.032, respectively). There was no statistically significant difference in mean depression scores between the groups with and without recovery, while the mean scores of anxiety and stress were statistically significant (p = 0.427, p = 0.012, p = 0.036, respectively).Conclusion: Anxiety and stress may be an etiologic factor and affect prognosis in SSHL.
Retrospective analysis of regional skin prick test results
(PLEKSUS BİLİŞİM TEKN.DANIŞ.TEMS.YAY.ORG.A.Ş., 2019) Kayabaşı, Serkan.; Kemeriz, Funda; Çayırlı, Serkan
In this study, we aimed to investigate the distribution of allergens in our region according to admission diagnosis and age inpatients and to determine the positivity rate in children and adults who underwent the skin prick test.Methods: The results of 300 patients who underwent the skin prick test were evaluated retrospectively, the skin prick test results wereinvestigated. Prick test positivity was compared between pediatric and adult patients.Results: Patients with the most positive response to the administered allergen extracts were found to be angioneurotic edema (75%) andallergic rhinitis patients (63.75%). The allergens with the highest positivity were determined to be the tree and shrub pollen (53.74%), housedust mites (53.06%), meadow and grass pollen (35.37%), respectively. Of the 300 patients who required the prick test, 80 (26.6%) wereallergic rhinitis, 65 (21.6%) were chronic cough, 58 (19.3%) were chronic idiopathic urticaria, 45 (15%) were generalized pruritus, 24 (8%)were atopic dermatitis, 18 (6%) were contact dermatitis, 6 (2.3%) were allergic asthma and 4 (1%) were angioneurotic edema patients. Thehighest test positivity in the pediatric patient population was in patients with allergic rhinitis (70.3%) and atopic dermatitis (48%). Prick testpositivity and multiple allergen positivity rates were not observed to be significantly different between children and adults (p> 0.05).Conclusion: Allergic rhinitis was found to be the most common prick test indication. Patient groups with the highest prick test positivitywere angioneurotic edema and allergic rhinitis. Tree and shrub pollens were the most common allergens.
The comparison of readability between information texts from web sites of private clinics and private hospitals
(İnönü University, 2019) Kuzucu, İhsan
Rhinoplasty is a surgery which can be done in state hospitals, private hospitals and private clinics. Patients gen-erally go tothe most suitable clinic whereas most surgeons prefer to perform surgery in private clinics. Thus, patients often confuse where toattend. Social media plays a crucial role for patients to decide where and who to choose. We compared readability of the informationtext from internet pages of private clinics and private hos-pitals from both plastic surgeons and otorhinolaryngologists.Material and Methods: The word “Rhinoplasty” was searched through internet and first 30 web sites were taken into account. First100 words from information texts about rhinoplasty from both private clinic and hospital web sites were copied and studied using aprogram called LIDA. Gunnig-Fog index, Flesch-Kincaid and Atesman values were noted and evaluated.Results: The readability of both private hospitals and private clinics were found to be hard. Flesch-Kincaid values showed thatinformation texts from private clinics in web sites (23.24 ± 3.45) were significantly different (p=0,035) than private hospitals (25,19± 3,5). As believed to be more specific to Turkish, Atesman values in private clinics (48,58 ± 16,71) were found to be more readablethan private hospitals (38.81 ± 18.06) (p=0,034).Conclusion: Comparison of information texts between private clinics and private hospitals of plastic surgeons and otorhinolaryngologists showed that Atesman values, which are believed to be more specific to Turkish, and Flesch-Kincaid values weresignificantly high in private clinics suggesting it is easier to understand. To sum it up, infor-mation texts guide patients to privatecritics.
Miringoplastide Greft Materyali Olarak Temporal Kas Fasyası ve Konkal Kıkırdak Kullanımının Erken ve Geç Dönem Anatomik ve Fonksiyonel Karşılaştırılması
(Alanya Alaaddin Keykubat Üniversitesi, 2019) Güler, İsmail; Baklacı, Deniz; Kuzucu, İhsan; Kum, Rauf Oğuzhan; Özcan, Müge
Timpanik membran perforasyonlarının onarımı için uygulanan miringoplasti ameliyatlarında temporal kas fasyası (TKF) ve konkal kıkırdak (KK) greftlerinin erkenve geç dönem anatomik ve fonksiyonel sonuçları karşılaştırıldı. Gereç ve Yöntemler: Çalışmaya kliniğimizde Nisan 2016 - Nisan 2018 tarihleri arasında opere edilen toplam 110 miringoplasti hastası dahil edildi. Her hasta için yaş, cinsiyet, greft materyali (TKF/KK), preoperatif ve postoperatif işitme seviyeleri,greft başarısı ve fonksiyonel başarı (hava-kemik aralığı < 10 dB) kaydedildi .Bulgular: Erken dönem greft başarısı açısından TFK (%93.5) ve KK (%93.8) gruplarıarasında anlamlı bir fark yoktu. (p= 0.966). Geç dönem greft başarısı açısından TFK(%85.5) ve KK (%91.7) grupları arasında anlamlı bir fark yoktu. (p= 0.319). Erkendönem fonksiyonel başarı açısından TFK (%87.1) ve KK (%85.4) grupları arasında anlamlı bir fark yoktu. (p= 0.799). Geç dönem fonksiyonel başarı açısından TFK(%82.3) ve KK (%83.3) grupları arasında anlamlı bir fark yoktu. (p= 0.882).Sonuç: Çalışmamızın sonucu TKF ve KK greftlerinin erken dönemde benzer başarı oranlarına sahip olduğunu gösterdi. Konkal kartilaj, geç dönem greft başarı oranının yüksek olması ve işitme üzerinde olumsuz bir etkisi olmaması nedeniyle primer miringoplastide güvenle tercih edilebilir.

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