A novel prognostic biomarker for recurrent aphthous stomatitis: Calprotectin
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Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cambridge University Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective. This study aims to investigate whether there is a correlation between serum calprotectin concentration and oral ulcer activity in patients with active recurrent aphthous stomatitis. Method. This prospective, cross-sectional, historical cohort study included 52 patients (26 with active lesions and 26 with inactive lesions) with recurrent aphthous stomatitis and 27 healthy volunteers. The relationship between the groups was statistically evaluated in terms of serum calprotectin level and other inflammatory parameters. Results. The median calprotectin value of the active lesion group (803 ng/ml) was significantly higher than that of the control group (55.4 ng/ml, p = 0.002). Furthermore, the median calprotectin value of the active lesion group was significantly higher than that of the inactive lesion group (72.5 ng/ml, p = 0.017). Conclusion. In patients with recurrent aphthous stomatitis and active ulcer lesions, the serum calprotectin value can be used as a reliable and robust prognostic marker for inflammation.
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Açıklama
Anahtar Kelimeler
Stomatitis, Aphthous, Leukocyte L1 Antigen Complex, Inflammation
Kaynak
Journal of Lartngology and Otology
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
133
Sayı
8
