Newly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery

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dc.authoridMujtaba, Muhammad -- 0000-0001-8392-9226; Sargin, Idris -- 0000-0003-3785-9575; Kaya, Murat -- 0000-0001-6954-2703
dc.contributor.authorMujtaba, Muhammad
dc.contributor.authorSargın, İdris
dc.contributor.authorAkyüz, Lalehan
dc.contributor.authorCeter, Talip
dc.contributor.authorKaya, Murat
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:14:54Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:14:54Z
dc.date.issued2017
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractSporopollenin microcages were produced from the pollens of Platanus orientalis. Paracetamol was loaded into the microcages. Pollen, sporopollenin, paracetamol and paracetamol-loaded sporopollenin microcages were characterized with FT-IR, TGA and SEM. The analytical analyses demonstrated that sporopollenin microcages were structurally intact, highly reticulated and thermally stable. The loading efficiency of the sporopollenin microcages was found to be 8.2% using the passive loading technique and 23.7% via evaporating loading technique. In vitro release and kinetics studies were performed to test the suitability of sporopollenin microcages for loading. These studies revealed that sporopollenin from P. orientalis can be suggested as a suitable carrier for drug loading and controlled release studies. (C) 2017 Published by Elsevier B.V.
dc.description.sponsorshipScientific and Technological Research Council of Turkey - Graduate Scholarship Programme for International Students [TUBITAK 2215]
dc.description.sponsorshipThe first author would like to thank The Scientific and Technological Research Council of Turkey for supporting him during this study under the program number TUBITAK 2215 - Graduate Scholarship Programme for International Students.
dc.identifier.doi10.1016/j.msec.2017.02.176
dc.identifier.endpage270en_US
dc.identifier.issn0928-4931
dc.identifier.issn1873-0191
dc.identifier.pmid28532028
dc.identifier.scopusqualityN/A
dc.identifier.startpage263en_US
dc.identifier.urihttps://doi.org/10.1016/j.msec.2017.02.176
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4199
dc.identifier.volume77en_US
dc.identifier.wosWOS:000403381200030
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Science Bv
dc.relation.ispartofMaterials Science & Engineering C-Materials for Biological Applications
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRelease Kinetics
dc.subjectDrug Delivery
dc.subjectMicrocapsule
dc.subjectAcetaminophen
dc.titleNewly isolated sporopollenin microcages from Platanus orientalis pollens as a vehicle for controlled drug delivery
dc.typeArticle

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