Assessing Algerian Ilex aquifolium L.’s phenolic compounds, antioxidant and enzyme inhibitory properties to find a new natural remedy for Alzheimer’s, diabetes and skin diseases
Loading...
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor & Francis
Access Rights
info:eu-repo/semantics/embargoedAccess
Abstract
This research explored the impact of methanolic extracts from the fruits and leaves of Ilex aquifolium L., a rare Algerian species, on several enzymes, focusing on tyrosinase, ?-amylase, ?-glucosidase, and cholinesterases, as well as their antioxidant potential in vitro assays, including phosphomolybdenum, DPPH, ABTS, CUPRAC, FRAP, and MCA. HPLC-DAD analysis identified chlorogenic acid, rosmarinic acid, hesperidin, and quercetin as predominant phenolic components. Both extracts exhibited notable antioxidant properties, up to 250.08?mg TE/g for fruits and 237.08?mg TE/g for leaf extracts. Enzyme inhibitory assays demonstrated significant inhibition against AChE and BChE with maximum activities of 2.34?mg GALAE/g in leaves and 4.32?mg GALAE/g in fruits. Additionally, considerable tyrosinase inhibition was observed in leaves at 39.69?mg KAE/g. These findings highlight I. aquifolium L. as a valuable source for investigating natural antioxidants and enzyme inhibitors, particularly for possible cosmetics and food additives applications.
Description
Keywords
Ilex Aquifolium L, Bioactive Compounds, Antioxidant Activity, Enzyme Inhibition Effect
Journal or Series
Natural Product Research
WoS Q Value
Scopus Q Value
Q1
