Association Between Plasma Sclerostin Levels and Body Mass Index in Women With Polycystic Ovary Syndrome
| dc.contributor.author | Bertizlioğlu, Mete | |
| dc.date.accessioned | 2024-05-06T12:42:44Z | |
| dc.date.available | 2024-05-06T12:42:44Z | |
| dc.date.issued | 2023 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | Polycystic ovary syndrome (PCOS) is recognized as one of the most common endocrine pathologies in females of reproductive age worldwide. This study investigated the relationship between serum sclerostin levels and body mass index (BMI) in women with PCOS.MethodsWomen aged 18-40 years who presented to our clinic between January 1, 2019, and January 1, 2020, and were diagnosed with PCOS were included in this study. The patients' clinical and laboratory data were recorded, and waist circumference, hip circumference, and BMI values were calculated. The patients with a BMI of >25 kg/m(2) were evaluated as Group I, those with a BMI of <18.5 kg/m(2) as Group II, and those with a BMI of 18.5-25 kg/m(2) as Group III. Serum sclerostin levels were compared between the BMI groups.ResultsThe study included 90 patients. The mean BMI values were 32.2 +/- 2.1, 17.0 +/- 0.9, and 22.9 +/- 2.1 kg/m(2) for Groups I, II, and III, respectively. We detected a statistically significant difference in serum sclerostin levels between Group II and Group I (p<0.005). There was a significant, positive correlation between the sclerostin level and BMI (r=0.258, p=0.014), weight (r=0.237, p=0.044), waist measurement (r=0.225, p=0.045), and hip measurement (r=0.225, p=0.033).ConclusionThis study revealed that abnormal body composition in PCOS could alter circulating sclerostin levels. | |
| dc.identifier.doi | 10.7759/cureus.48875 | |
| dc.identifier.issn | 2168-8184 | |
| dc.identifier.issue | 11 | en_US |
| dc.identifier.uri | https:/dx.doi.org10.7759/cureus.48875 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/11782 | |
| dc.identifier.volume | 15 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Cureus, Inc. | |
| dc.relation.ispartof | The Cureus Journal of Medical Science | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Women | |
| dc.subject | Sclerostin | |
| dc.subject | Polycystic Ovary Syndrome | |
| dc.subject | Patients | |
| dc.subject | Body Mass Index | |
| dc.title | Association Between Plasma Sclerostin Levels and Body Mass Index in Women With Polycystic Ovary Syndrome | |
| dc.type | Article |
