Autologous biological vitamin-C-added (ABC) Filler for facial volume restoration

dc.authorid0000-0003-2966-6618
dc.contributor.authorÖzer, Kadri
dc.contributor.authorAtan, Oğuz
dc.contributor.authorÇolak, Özlem
dc.date.accessioned2021-07-05T10:33:58Z
dc.date.available2021-07-05T10:33:58Z
dc.date.issued2021
dc.departmentTıp Fakültesi
dc.description*Atan, Oğuz ( Aksaray, Yazar )
dc.description.abstractPurpose: Face rejuvenation procedures with injectable agents continue to gain popularity. Nowadays, a variety of commercial products are available as filler material. Ideal fillers should be inexpensive, easily obtainable, nontoxic, and biocompatible. The aim of this study is to report a clinical perspective for an appropriate, feasible, and inexpensive protocol of a stable, autologous biological filler for facial volume restoring without any commercial kits. Methods: Eight patients were investigated who underwent facial injection with ABC filler. Eleven ml of whole blood was placed in standard tubes containing anticoagulant and for each patient, 8 tubes were prepared. After the centrifugation at 1630 xg for 5 minutes, the upper plasma was taken, calcium was added and cooled. After the addition of vitamin C, the syringes were incubated at 85 °C for 10 minutes. The autologous biological material obtained was used as filling material. For comparison, FACE-Q satisfaction questionnaires were used before and after the procedure. Results: All patients were followed up for a minimum of 4 months. No major complications were recorded. The patient-reported FACE-Q satisfaction and FACE-Q quality of life pre- and post-procedure results showed statistically significant improvement (p < 0.05). Overall satisfaction with the outcome was 89.12 ± 16.73 (range 55–100). Conclusions: ABC filler can be seen as a reliable, inexpensive, and easily obtainable material to restore facial volume with increased patient satisfaction and quality of life scores. We believe that our study will be encouraging to the application of autologous biological fillers for further clinical and scientific studies.
dc.identifier.doi10.1007/s00266-021-02297-1
dc.identifier.endpage-en_US
dc.identifier.issn0364-216X
dc.identifier.issue-en_US
dc.identifier.pmid33973050
dc.identifier.scopusqualityQ1
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/10.1007/s00266-021-02297-1
dc.identifier.urihttps://hdl.handle.net/20.500.12451/8320
dc.identifier.volume-en_US
dc.identifier.wosWOS:000648822600003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofAesthetic Plastic Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAutologous
dc.subjectBiological
dc.subjectFiller
dc.subjectPlasma
dc.subjectWrinkles
dc.titleAutologous biological vitamin-C-added (ABC) Filler for facial volume restoration
dc.typeArticle

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