Determination of the effect of Tarantula cubensis alcoholic extract on cadmium embryotoxicity

dc.authorid0000-0001-7100-4437
dc.authorid0000-0001-5949-4752
dc.authorid0000-0002-9027-4229
dc.authorid0000-0002-4079-500X
dc.authorid0000-0003-3660-0721
dc.contributor.authorCanbar, Rahmi
dc.contributor.authorAkçakavak, Gökhan
dc.contributor.authorUslu, Muhittin
dc.contributor.authorArslan, Mustafa Sedat
dc.contributor.authorKızılay, Harun
dc.date.accessioned2025-07-11T08:22:52Z
dc.date.available2025-07-11T08:22:52Z
dc.date.issued2025
dc.departmentVeteriner Fakültesi
dc.description.abstractTarantula cubensis alcoholic extract (TCAE) is a homeopathic product used in the veterinary field. This study aimed to determine the effects of TCAE on cadmium (Cd) toxicity in the embryo. The study used 220 fertile, incubated chicken eggs divided into 11 equal groups on the 7th day of incubation. The groups comprised untreated and physiological saline control groups, a group with TCAE alone, four groups with varying doses of Cd alone and four groups with the same doses of Cd plus TCAE. At the end of the incubation period, the eggs were opened, kidney and liver tissue samples were taken for histopathology and the number of dead and living embryos were recorded. In the prsent study, the median lethal dose of Cd was determined to be 0.029 mg per egg and the median lethal dose of Cd plus TCAE was determined to be 0.020 mg per egg. The histopathological examinations determined that kidney and liver damage were increased when TCAE and Cd were administered together, that was higher than when Cd was given alone. Thus, TCAE, which had no toxic effect on the embryo when used alone, might increase the embryotoxic activity of Cd. However, more detailed studies are needed.
dc.identifier.doi10.30466/vrf.2024.2031444.4313
dc.identifier.endpage208
dc.identifier.issn20088140
dc.identifier.issue4
dc.identifier.scopus105003405389
dc.identifier.startpage203
dc.identifier.urihttps://dx.doi.org/10.30466/vrf.2024.2031444.4313
dc.identifier.urihttps://hdl.handle.net/20.500.12451/13260
dc.identifier.volume16
dc.identifier.wosWOS:001476280000003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAkçakavak, Gökhan
dc.institutionauthorid0000-0001-5949-4752
dc.language.isoen
dc.publisherUrmia University - Faculty of Veterinary Medicine
dc.relation.ispartofVeterinary Research Forum
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCadmium
dc.subjectEmbryotoxic
dc.subjectIn Ovo Methods
dc.subjectTarantula Cubensis Alcoholic Extract
dc.titleDetermination of the effect of Tarantula cubensis alcoholic extract on cadmium embryotoxicity
dc.typeArticle

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