Monocyte-to-HDL-cholesterol ratio is associated with ascending aorta dilatation in patients with bicuspid aortic valve

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dc.contributor.authorAcar, Burak
dc.contributor.authorYayla, Çağrı
dc.contributor.authorGül, Murat
dc.contributor.authorKaranfil, Murat
dc.contributor.authorÜnal, Sefa
dc.contributor.authorUçar, Fatih
dc.contributor.authorKuyumcu, Serdar Mevlüt
dc.contributor.authorErtem, Ahmet Göktuğ
dc.contributor.authorÖzen, Yasin
dc.contributor.authorÖzbay, Mustafa Bilal
dc.contributor.authorÖzeke, Özcan
dc.contributor.authorAydoğdu, Sinan
dc.date.accessioned2021-06-24T19:28:52Z
dc.date.available2021-06-24T19:28:52Z
dc.date.issued2021
dc.departmentTıp Fakültesi
dc.description*Gül, Murat (Aksaray, Yazar )
dc.description.abstractBackground: The importance of monocyte count-to-HDL-cholesterol ratio (MHR) in cardio- vascular diseases has been shown in various studies. Ascending aortic dilatation (AAD) is a common complication in the patients with bicuspid aortic valve. In this study, we aimed to investigate the relationship between MHR and the presence of aortic dilatation in the patients with bicuspid aortic valve. Methods: The study population included totally 347 patients with bicuspid aortic valve.169 patients with aortic dilatation (ascending aorta diameter ? 4.0 cm) and 178 patients with no aortic dilatation. Echocardiographic and laboratory measurement was done and compared between groups. Results: The mean age of the participants was 44.7 ± 15.4 years and average ascending aorta diameter was 3.2 ± 0.3 cm in dilatation negative group and 4.4 ± 0.4 cm in positive group. MHR was significantly increased in in patients with aortic dilatation. MHR and uric acid level was independently associated with the presence of aortic dilatation in the patients with bicuspid aortic valve. Conclusion: We found a significant relationship between MHR and aortic dilatation in the patients with bicuspid aortic valve.
dc.identifier.doi10.4314/ahs.v21i1.14
dc.identifier.endpage104en_US
dc.identifier.issn1680-6905
dc.identifier.issue1en_US
dc.identifier.pmid34394286
dc.identifier.scopusqualityQ2
dc.identifier.startpage96en_US
dc.identifier.urihttps:/dx.doi.org/10.4314/ahs.v21i1.14
dc.identifier.urihttps://hdl.handle.net/20.500.12451/8176
dc.identifier.volume21en_US
dc.identifier.wosWOS:000677673800013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMakerere University, Medical School
dc.relation.ispartofAfrican Health Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAorta Aneurysm
dc.subjectBicuspid Aorta
dc.subjectInflammation
dc.subjectMonocyte HDL Ratio
dc.titleMonocyte-to-HDL-cholesterol ratio is associated with ascending aorta dilatation in patients with bicuspid aortic valve
dc.typeArticle

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