Evaluation of biological activity and antioxidant capacity of Turkish licorice root extracts
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Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Glycyrrhiza glabra L. (Licorice) is a well-known medicinal herb that grows in various parts of the world. In the current study, the antimicrobial activities of n-hexane and dichloromethane extracts from G. glabra root were investigated by using the disc-diffusion and microdilution-broth methods against human and fish pathogen microorganisms. The antioxidant activities of the extracts were determined with total antioxidant activity, DPPH activity, ferric ion reducing power and CUPRAC assay. The total phenolic compounds and flavonoids were also studied for the extracts. In antimicrobial screening, G. glabra root extracts showed potent antimicrobial activity against all the tested clinical and food-borne pathogenic microorganisms. Streptococcus agalactiae exhibited a higher sensitivity against the dichloromethane extract with the highest zone diameter (18.21 mm) and the lowest MBC value (1.41 mg/ml) of all the fish pathogens. On the other hand, the free radical scavenging activities of n-hexane and dichloromethane extracts were found as IC50 579.98 µg/ml and 111.49 µg/ml, respectively. The results showed that the root dichloromethane extract has a stronger antioxidant capacity compared with n-hexane extract. The findings indicated the potential use of the n-hexane and dichloromethane extracts from G. glabra root as biopreservatives as they demonstrated high antimicrobial and antioxidant activities. © 2014 University of Bucharest.
Description
Keywords
Antibacterial, Antifungal, Dichloromethane, Fish pathogen, Human Pathogen, N-hexane
Journal or Series
Romanian Biotechnological Letters
WoS Q Value
N/A
Scopus Q Value
N/A
Volume
19
Issue
1
