An ex vivo experimental study comparing the effects of the holmium: yttrium–aluminum-garnet and thulium fiber lasers on testicular tissue

dc.contributor.authorKaraaslan, Mustafa
dc.contributor.authorYılmaz, Mehmet
dc.contributor.authorOrdu, Melike
dc.contributor.authorŞirin, Mehmet Emin
dc.date.accessioned2025-04-22T07:33:47Z
dc.date.available2025-04-22T07:33:47Z
dc.date.issued2025
dc.departmentTıp Fakültesi
dc.description.abstractThe effects of lasers on testicular tissue have not yet been investigated in detail. In this experimental ex vivo study, we aimed to demonstrate and compare the effects of the holmium:yttrium–aluminum-garnet (Ho:YAG) and thulium fiber laser (TFL) lasers on testicular tissue. An ex vivo experiment was performed using calf testes. A 100W Ho:YAG laser and a 60W TFL devices with a setting spectrum at 10–60W, a frequency of 20–40 Hz, energy levels at 0.5–1–1.5 J, and medium pulse duration were tested. Histopathological parameters such as Incision depth (ID), vaporization area (VA), coagulation area (CA), and total laser area (TLA = VA + CA) were evaluated. In testicular tissue without a tunica layer, a statistically significant difference was found in the mean VA and TLA values between the Ho:YAG and TFL, in favor of Ho:YAG (p = 0.003, p = 0.003, respectively). In testicular tissue with a tunica layer, there was a statistically significant difference in mean VA, CA, TLA, ID values between Ho:YAG and TFL, in favor of Ho:YAG (all p < 0.001). At 1.5 J–20 Hz and 1.5 J–40 Hz, we observed that the features indicating tissue dissection, such as VA and ID, were lower in the TFL than those in Ho:YAG, while CA values were higher. VA, CA, TLA, ID values were significantly increased in tissue with tunica compared to non-tunicated tissue in both the Ho:YAG and TFL applications. At 30W and 60W, the penetrative effect of the TFL on tissue was less than that of the Ho:YAG, but its coagulation property was superior. (Table presented.)
dc.identifier.doi10.1007/s10103-025-04388-w
dc.identifier.issn02688921
dc.identifier.issue1
dc.identifier.pmid40080218
dc.identifier.scopus2-s2.0-105000024842
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://dx.doi.org/10.1007/s10103-025-04388-w
dc.identifier.urihttps://hdl.handle.net/20.500.12451/13095
dc.identifier.volume40
dc.identifier.wos001444463400001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorŞirin, Mehmet Emin
dc.language.isoen
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.relation.ispartofLasers in Medical Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectHolmium Laser
dc.subjectTestes
dc.subjectTFL
dc.subjectTissue Effect
dc.titleAn ex vivo experimental study comparing the effects of the holmium: yttrium–aluminum-garnet and thulium fiber lasers on testicular tissue
dc.typeArticle

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