Some predictive ındexes are potentially promising clinical parameters in dogs with primary cholangitis-cholangiohepatitis

Basit Öğe Kaydı
dc.authorid0000-0003-2789-035X
dc.contributor.authorÇolakoğlu, Ekrem Çağatay
dc.contributor.authorAydemir, Melek
dc.contributor.authorSevim, Kadir
dc.contributor.authorHaydardedeoğlu, Ali Evren
dc.contributor.authorKaya, Ufuk
dc.date.accessioned2025-09-17T12:51:57Z
dc.date.available2025-09-17T12:51:57Z
dc.date.issued2025
dc.departmentVeteriner Fakültesi
dc.description.abstractThe invasive nature of liver biopsy and the risk of complications make patients reluctant to undergo the procedure. This situation has necessitated the search for easily accessible haematological indexes such as neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width to lymphocyte ratio (RDW/LYM) to contribute to the clinical diagnosis and prognosis evaluation processes in dogs with cholangitis-cholangiohepatitis. Objectives: The aim of the study is to evaluate some predictive markers to contribute the clinical diagnosis in dogs with cholangitis-cholangiohepatitis. Medhods: Seventeen client-owned dogs with cholangitis-cholangiohepatitis were randomly allocated. Nine clinically healthy dogs (control group) confirmed with clinical examination, complete blood count (CBC) and serum profiles were used. Cholangitis-cholangiohepatitis was diagnosed in dogs with dilated bile ducts, thickened gallbladder wall up to 4 mm and increased parenchymal echogenicity. Clinical procedures including clinical examination, blood analyses and diagnostic abdominal ultrasonography were performed in all dogs. CBC indices such as NLR, mean platelet volume to platelet ratio (MPV/PLT), red cell distribution width to platelet ratio (RDW/PLT), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR) and RDW/LYM were calculated using absolute CBC values. Results: A final total of 10 dogs were enrolled in the study. NLR and RDW/LYM ratios were significantly higher (p < 00.5) in dogs with cholangitis-cholangiohepatitis compared to healthy ones. Conclusion: The results of this study suggest that the use of NLR and RDW/LYM ratio in dogs with cholangitis-cholangiohepatitis complex appears potentially promising. Larger prospective, case-control studies are needed to further evaluate these findings. Veterinary practitioners can obtain valuable diagnostic data before possible invasive liver procedures by evaluating NLR and RDW/LYM ratios, which are easily obtained from CBC parameters.
dc.identifier.doi10.1002/vms3.70559
dc.identifier.issn20531095
dc.identifier.issue5
dc.identifier.scopus2-s2.0-105012929100
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1002/vms3.70559
dc.identifier.urihttps://hdl.handle.net/20.500.12451/14443
dc.identifier.volume11
dc.identifier.wosWOS:001549642100001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAydemir, Melek
dc.institutionauthorHaydardedeoğlu, Ali Evren
dc.language.isoen
dc.publisherWiley-Blackwell Publishing Ltd
dc.relation.ispartofVeterinary Medicine and Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCholangitis
dc.subjectDog
dc.subjectLymphocyte
dc.subjectNeutrophil
dc.subjectRed Cell Distribution Width
dc.titleSome predictive ındexes are potentially promising clinical parameters in dogs with primary cholangitis-cholangiohepatitis
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
colakoğlu-ekrem cağatay-2025.pdf
Boyut:
164.25 KB
Biçim:
Adobe Portable Document Format
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu