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Öğe Relationship between blood antioxidant paraoxo-nase-1 and the offspring yield in hair goats(Trakia University, 2024) Dursun, ŞükrüSmall ruminants bring unproductive pastures to the economy with products such as meat and milk. Although the management of Hair goats is difficult compared to that of sheep, they make better use of unproductive pastures than sheep. The birth rate of Hair goats is high, but the multiple birth rate is quite low. This study aimed to determine the relationship between the antioxidant paraoxonase-1 (PON-1), and the offspring yield in Hair goats. In the second week of September, 100 females were randomly selected and blood samples were taken 15 days before the introduction of male goats to the herd from both males and females. Blood was taken from the same animals again before starting milk-ing in May. Paraoxonase-1 values were found to be low and significantly different in both sexes in October compared to May. There was a statistical difference (P?0.05) in PON-1 level in terms of gender and birth type. The PON-1 level of Hair goats that gave birth to twins was like that of male goats and goats with single birth, while it was insignificant between single-birth and infertile goats. It was found that a low PON-1 value was associated with low fertility whereas twin births were closely related to high value of PON-1. PON-1 was found to be important for multiple births (P?0.05). As a result, it was concluded that the PON-1 level increased the birth rate and offspring yield in Hair goats.Öğe Primary bone tumors in dogs and cats: 98 cases(Veteriner Hekimler Derneği, 2024) Filikci, Kürşat; Sağlam, Mehmet; Kutsal, Osman; Tunc, Arda SelinThe aim of this study is to contribute to the current literature by determining the distribution of bone tumors in dogs and cats by breed, age, gender and location. Bone tumors are more common in dogs than cats, and the most common primary bone tumor in both species is osteosarcoma. The biopsy and necropsy reports of the Ankara University, Faculty of Veterinary Medicine, Department of Pathology , were retrospectively studied examining for cases of primary bone tumors in dogs and cats. This study's period encompassed from 2001 through 2020 (20 years). A total of 98 bone tumors were detected 70 in dogs and 28 in cats. Of the cases in dogs, 13 (18.57%) were necropsy, while 57 (81.43%) were biopsy. Sex distribution of bone tumors is in female dogs (n:28, 40%) and in male dogs (n:38, 54.29%). Also, females (n:17, 60.7%) and males (n:11, 39.3%) were observed in cats. in dogs, although 57.14% (n=40) were purebreds and 31.43% (n=22) were mongrel breeds, in cats, 75% of them were mongrel (n=21) and 7.1% (n=2) were purebred. While locations of tumors in dogs were appendicular (65.71%, n=46), axial (30%, n=21), locations of tumors in cats were appendicular (50%, n=14), axial (39.29%, n=11) and both appendicular and axial (10.71%, n:3). While 13 benign (18.57%) and 57 malignant (81.43%) tumors were observed in dogs, 4 benign (14.29%) and 24 malignant (85.71%) tumors were observed in cats. The data were analyzed in the SPSS program and no significant relationship was detected between the data (P>0.05). This study would contribute and conduce the comparative oncology for dogs and cats.Öğe A review of surgical cases of newborn calves.(Ebubekir CEYLAN, 2024) Avcı, Nihan; Gümüş, Fehmiye; Boztok Özgermen, Başak; Sağlam, MehmetThis study aimed to retrospectively evaluate the diseases of calves. Surgically encountered diseases, causes, indicated treatment methods, and possible complications were evaluated and it was thought to contribute to scientific and clinical studies on this subject. Material-Method: The material of this study consisted of a total of 150 calves of different breeds, ages, and sexes brought to Aksaray University Faculty of Veterinary Medicine Animal Hospital Surgery Clinic between December 2017 and 2023 due to various problems. Result: In terms of surgical diseases, 37.3% of 150 calves were soft tissue, 56.6% orthopedics, 2% ophthalmology, and 4% neurology cases. Congenital anomalies were found in 44.65% of 56 patients with soft tissue disease. Orthopedic examination revealed, 57.1% of the cases had fractures, 23.8% had arthritis and 19% had tendon diseases. It was determined that 37.3% of the surgical cases between 2017 and 2023 were soft tissue-related. In addition to soft tissue diseases, there were 5 ophthalmologic cases, including orbital mass (n=2) and dermoid cyst (n=3) Conclusion Finally, while cattle breeding has great economic importance in our country, calf losses occur due to economic conditions such as artificial insemination errors, irregular registration systems, lack of standardization of care and housing, incorrect intervention of the patient owner, and treatment costs. It is envisaged that economic losses will be minimized with early diagnosis, early intervention, appropriate medical treatment, and surgical treatment options.Öğe Relationship between growth performance, passive immunity and health In preweaned lambs(Erciyes Üniv. Veteriner Fakültesi, 2024) Gökçe, Orhan; Ayvazoğlu, Cemalettin; Cihan, Pınar; Atakişi, Onur; Kırkızıgül, Ali Haydar; Erdoğan, Hidayet MetinThis study was designed to investigate associations between transfer of passive immunity, selected illness-es (diarrhoea, pneumonia, and fatigue anorexia syndrome-FAS) and growth performance [body weight (BW) and aver-age daily gain (ADG)] in preweaned lambs. A total of 347 lambs were blood sampled at 24±1 h of age after birth and the serum IgG concentration for each lamb was measured after colostrum intake using a commercial ELISA kit. Lambs were weighed on a scale immediately after birth (before colostrum intake) and reweighed on day 28 (end of neonatal period) and day 84 (age of weaning). Lambs ADG was calculated from 0 to 28 d of life, from 29 to 84d of life, and from 0 to 84 d of life. Growth performance (BW and ADG) of lambs with diarrhoea and FAS in the neonatal period and with pneumonia in the postneonatal period was significantly lower than that of healthy lambs of the same period (P<0.05). BW of lambs with serum IgG concentration at 24th hour after the birth (SIgGC-24)<600 mg/dL and <1000 mg/ml was significantly lower on days 28 and 84 than that of lambs with SIgGC-24 >600 mg/dL and >1000 mg/ml (P<0.001). Simi-larly, the ADG of lambs with SIgGC-24 <600 mg/dL and <1000 mg/ml was significantly lower on days from 0-28, 29-84 and 0-84 of age than those of lambs with SIgGC-24 >600 mg/dL and >1000 mg/ml (P<0.001). In conclusion, our find-ings show that low serum IgG concentration in lambs, as well as the presence of pneumonia, diarrhea and FAS, reduc-es growth performance in pre-weaning lambs.Öğe Histiocytic sarcoma complex in the palpebral conjunctiva of a seven-month-old dog(Universiteit Gent, 2024) Avcı, Nihan; Gümüş, F.; Boztok Özgermen, B.; Yavuz, O.A seven-month-old, intact, female Anatolian Shepherd dog was referred for treatment of swelling and redness of the left eye. Ophthalmological examination revealed a pea-sized mass in the palpebral conjunctiva of the left lower eyelid. Ulcerative keratitis and blepharospasm were detected due to the irritation caused by the mass. Fluorescein staining was positive and the Schirmer tear test result was 13 mm/min. No other masses were detected in other parts of the patient’s body, and its general condition was good. The mass was removed surgically and was interpreted as histiocytic sarcoma. During a three-year, post-operative follow-up period, no recurrence of the mass was observed.Öğe The relationship between total thiol and pregnancy in hair goats(İlker ÇAMKERTEN, 2023) Dursun, ŞükrüIn order to increase increase fertility, hormonal application have been applied but, relationship between reproduction and stress/oxidant levels have not been investigated in hair goats. In this study, the relationship between increase fertility and TotalThiol levels were investigated in Hair Goats. 100 head female goats with a live weight of 45-50 kg at the age of 2-6 years and 20 heads of males with a live weight of 60-70 kg were used. In September, 100 females selected and marked, and blood samples were taken from all goats into anticoagulant tubes from vena jugularis 15 days before male introduction to the herd. Blood sampling was repeated from the same animals again before the start of lactation. Total Thiol values were found to be significant in October compared to May. It was determined that there was a difference (p?0.05) in the Total Thiol level in terms of sex and birth type. The Total Thiol level of twin-bearing hair goats was statistically different from the non-bearing hair goats while the total Thiol level in single-bearing hair goats was similar to those that gave birth to twins and those that did not. Goats with low Total Thiol value had a twin birth and goats with high Total Thiol value were have no birth. Total Thiol value was found to be important for multiple births (p?0.05). As a result, it was concluded that the Total Thiol level during the goat breeding season was related to birth rate and offspring yield in hair goats.Öğe Clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in dogs with infectious tracheobronchitis(İlker ÇAMKERTEN, 2023) Haydardedeoğlu, Ali Evren; Çolakoğlu, Ekrem Çağatay; Kaya, UfukCanine infectious tracheobronchitis (ITB) is a highly contagious disease of dogs expressed with remarkable respiratory signs. Therapy with antibiotics in canine ITB still remains questionable. The purpose of this study was to compare the clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in the treatment of canine ITB. Client-owned dogs with canine ITB signs (n=60) were enrolled in this prospective, controlled, and randomized blinded clinical trial. A computer-generated list randomization was employed to assign the dogs equally into the Group CLA: clarithromycin (25 mg/kg, PO), the Group AMX: amoxicillin and clavulanic acid (25 mg/kg, PO), the Group ENR: enrofloxacin (2.5 mg/kg, PO), and the Group DOX: doxycycline (5 mg/kg, PO). The administration of CLA alleviated the cough sign earlier than DOX. The recovery time of oculonasal discharge in group CLA were also earlier compared to the other groups. The tracheal sensitivity also disappeared earlier in the Groups CLA and AMX. In conclusion although there is no always statistically significance between groups, clarithromycin appears to be superior to other antibiotics suggesting that it can be the first antibiotic choice to alleviate the ITB signs in dogs.Öğe Antibiogram Results of Escherichia coli in Calf Diarrhea and Escherichia coli Bacteria in Aksaray Province in The Last Three Months(Afyon Kocatepe Üniv. Veteriner Fak., 2023) Haydardedeoglu, Ali Evren; Aydemir, Melek; Şenoğlu, Elif Selin; Aras, ZekiEscherichia coli is a gram-negative, facultative anaerobic, motile, non-spore-forming rod-shaped bacterium belonging to the Enterobacteriaceae family. Pathogenic E. coli are divided into two groups: extraintestinal and intestinal. Intestinal Escherichia coli pathotypes: enterotoxigenic E. coli (ETEC), enteropathogenic E. coli (EPEC), Vero- or Shiga-toxin-producing E. coli (VTEC or STEC), enterohemorrhagic E. coli (EHEC), enteroaggregative E. coli (EAEC), enteroinvasive E. coli (EIEC) and diffusely adherent E. coli (DAEC). Extraintestinal pathogenic E. coli: These can be listed as septicemic pathogenic E. coli, uropathogenic E. coli, avian pathogenic E. coli, breast pathogenic E. coli and those that cause uterine infections, endometrial pathogenic E. coli. Enterotoxigenic Escherichia coli (ETEC) is the most common cause of neonatal diarrhea in calves and is a bacterial disease that colonizes the small intestine, produces enterotoxin, and occurs among calves during the neonatal period. The aim of this study is to determine the E.coli isolates that cause neonatal calf diarrhea in the Aksaray region between January, February and March 2021. To be used in the study, internal organ samples (liver, heart, lung and mesenteric lymph node) of neonatal calves that died due to diarrhea were taken from 20 different cattle farms in the Aksaray region. One calf that died in each farm was included in the sampling, and a total of 20 calves were sampled. E.coli was isolated in 12 (60%) of the internal organ samples covering these three months. According to the antibiogram results of the samples, 50% of the isolates were converted to Amoxicillin and Erythromycin, 33.3% to Tetracycline, 58.3% to Trimethoprim-sulfamethoxazole, 66.6% to Streptomycin, 75% to Flofenicol, Gentamicin and Enrofloxacin, % 83.3 of them were found to be sensitive to Cefloxacin and Cefloxacinium.Öğe The effect of oxidative stress on the reproductive performance in Hair Goats(Hellenic Veterinary Medical Society, 2023) Dursun, ŞükrüSmall ruminants make better use of pastures with low grass yield and poor vegetation and therefore con-tribute significantly to the country’s economy. In order to achieve maximum yield from these animals, it is necessary to optimize nutrition and minimize stress factors. Oxidative stress affects the normal functioning of many physiological systems including fertility. This study was carried out to determine oxidative stress with regard to effect of antioxidants on fertility in hair goat in October and May. In this study, oxidative stress index (OSI), total oxidation level (TOS) and total antioxidant (TAS) levels were investigated in 20 male and 100 female hair goats during the breeding season (October) and out-of-season (May). Females between the ages of 2-6 years and male hair goats aged 2-4 years were used in the study. The correlation between TAS, TOS, and OSI and fertility was evaluated according to gender and season. TAS, TOS and OSI values in female hair goats were 1.28 µmol/L, 1.34 µmol/L; and 11.02 µmol/L in October and 7.13 µmol/L; 0.87 µmol/L and 0.53 µmol/L in May, respectively; as for male hair goats 1.32 µmol/L, 1.44 µmol/L and 4.24 µmol/L in October and 8.84 µmol/L; 0.32 µmol/L, and 0.63 µmol/L in May, respectively. Seasonal differences between genders and calving and infertile groups were found (P=0,001). As a result, while the increase in TOS level causes a decrease in offspring yield in hair goats, it has been concluded that the increase in TAS level positively affects the offspring’s productivity.Öğe Autologous platelet-rich plasma treatment in a dog with vincristine extravasation injury(NLM (Medline), 2023) Boztok Özgermen, BaşakExtravasation of vincristine sulfate (VS) is a common complication encountered during canine transmissible venereal tumor treatment and other hematopoietic neoplasms, such as lymphoma and leukemias. The leakage of the chemotherapeutic agent may result in soft tissue damage leading to ulceration and necrosis. Studies have shown that platelet-rich plasma consists of growth factors and cytokines, thus plays a crucial role in wound healing. This study aimed to evaluate the effects of autologous platelet-rich plasma and antimicrobial wound dressing for the treatment of VS extravasation-related acute full-thickness skin wounds. A male Aksaray Malakli shepherd dog (3 years old) was brought to our clinic with a wound on the left forelimb which appeared two days after intravenous injection of VS. Extravasation was suspected. A total of 3.5 mL autologous platelet-rich plasma was injected into the wound margins and an antimicrobial dressing containing chlorhexidine acetate was used weekly to close the wound. The wound healed without any complications in 6 weeks. It was concluded that autologous platelet-rich plasma treatment is a simple and cost-effective method for the treatment of VS extravasation-related acute full-thickness skin wounds.Öğe Thoracoscopic partial pericardiectomy for the treatment of pericardial effusion in dogs(Ankara Üniversitesi Veteriner Fakültesi, 2023) Şen, Yusuf; Bumin, Ali; Okan Şenel, Oytun; Boztok Özgermen, Başak; Haydardedeoğlu, Ali Evren; Başer, Medine İremThoracoscopy is a minimally invasive imaging method used in the imaging of the thoracic cavity. In comparison with thoracotomy, thoracoscopy provides better visualization of even the smallest lesions localized in the thoracic cavity. With the use of thoracoscopy, the operation stress in the patient and tissue trauma are reduced, and operating time is shortened. The aim of this study was to evaluate 20 dogs with severe pericardial effusion, which manifested as severe circulation disorder and respiratory distress. The patients determined with pericardial effusion as a result of radiographic and echocardiographic examinations were applied with partial pericardiectomy to achieve permanent health and it was decided to apply this with the minimally invasive thoracoscopic method. The paraxiphoid-transdiaphragmatic approach was applied to the first ten patients and the intercostal approach to the latter. Applicability of thoracoscopic partial pericardiectomy, advantages compared to open surgery, differences between two approach techniques, disadvantages, complications, and success rates were evaluated. It was concluded that this procedure was a successful procedure for dogs and the transdiaphragmatic approach was more useful. In conclusion, thoracoscopic partial pericardiectomy was determined to be easy to apply and more advantageous than open thoracotomy operations.Öğe Aksaray Üniversitesi Veteriner Fakültesi iç hastalıkları kliniğine getirilen hastaların retrospektif değerlendirilmesi(Afyon Kocatepe Üniversitesi, 2022) Aydemir, Melek; Haydardedeoğlu, Ali Evren; Çamkerten, İlker; Erdoğan, Hidayet MetinBu çalışmada yeni kurulan fakültemiz hastanesine getirilen hastaların demografik analizleri amaçlanmıştır. Bu amaçla 23.06.2015-30.06.2021 tarihleri arasında Aksaray Üniversitesi Veteriner Fakültesi İç Hastalıkları Kliniği’ne tanı ve tedavi amacıyla getirilen hastalar çalışmaya dahil edildi. Toplam 657 hastanın retrospektif değerlendirilmesi yapıldı. Hastaların yıl, ay ve türlere göre dağılımları ile hastalıkların yerleştiği sistemlere göre sınıflandırılması yapıldı. Söz konusu yıllar arasında en fazla karnivor, en az kanatlı hastanın getirildiği belirlenmiştir. Hasta yoğunluğunun en fazla olduğu yıl 2021 ve en az ise 2015 yılı olarak kaydedilmiştir. Hayvan sayısının kış mevsiminde, özellikle Şubat ayında en yüksek orana ulaştığı, yaz mevsiminde ise Temmuz ayında en az olduğu belirlenmiştir. Sistem hastalıkları yönünden değerlendirildiğinde, tüm türlerde en çok sindirim sistemi ikinci sırada ise solunum sisteminin etkilendiği vakalar tespit edilmiştir.Öğe Investigation of changes in spermatozoon characteristics, chromatin structure, and antioxidant/oxidant parameters after freeze-thawing of hesperidin (Vitamin P) doses added to ram semen(MDPI, 2022) Yeni, Deniz; Güngor, Şükrü; Avdatek, Fatih; Gülhan, Mehmet Fuat; Olgaç, Kemal Tuna; İnanç, Muhammed Enes; Denk, Barış; Taşdemir, UmutWe conducted this study to determine the potential cryopreservative effects of different hesperidin (vitamin P; H) doses on ram semen after freeze-thawing. Semen samples were obtained from Sonmez rams using an artificial vagina. The samples were divided into six groups: control, 10, 50, 100, 250, and 500 mu g/mL H (C, H10, H50, H100, H250, and H500, respectively). At the end of the study, sperm motility and kinetic parameters, acrosome integrity (AI), mitochondrial membrane potential (MMP), viability, lipid peroxidation levels (LPL), chromatin damage, oxidant parameters, and antioxidant parameters were assayed. None of the doses of H added to the semen extender showed any enhancing effects on progressive motility compared to C (p > 0.05). In fact, H500 had negative effects (p < 0.05). Moreover, AI was the highest at the H10 dose, while LPL values were the lowest at the same dose (p < 0.05). The doses of H10 and H50 added to the Tris extender medium showed positive effects on sperm cell chromatin damage. Consequently, we can say that H doses used in this study are not effective on semen progressive motility, but the H10 dose is effective on AI and chromatin damage by reducing LPL.Öğe Operative treatment of splint bone fractures in horses(Ankara Üniversitesi Veteriner Fakültesi, 2022) Sağlam, Mehmet; Yardımcı, CenkIn this study; it is aimed to present the operative treatment and results, which are indicated for the continue of their racing life in splint bone fractures which are frequently occurred in race horses. The 2nd and 4th metacarpal (Mc-II and Mc-IV) and metatarsal bones (Mt-II and Mt-IV) of the horse are accessory structures that support the carpus and tarsus. Fractures of these bones in horses are called “splint bone fractures”. Splint bone fractures are relatively common in horses and usually seen in forelimbs. Fractures of the proximal part are rarer and represent 2.7-5% of all splint bone fractures, but challenging to manage. In the present study, 5 cases of splint bone fractures in different horses were evaluated. The distribution of the fractures were Mc-II in three, Mc-IV and Mt-IV in one each. Localization of the fractures were distal 1/3 in 4 and diaphyseal in 1 horse. For the management of these fractures, surgical removal of the fractured fragments were performed under general anaesthesia. Functional limb usage was achieved following the 30th day postoperatively in all cases.Öğe Circulating miRNAs in maternal plasma as potential biomarkers of early pregnancy in sheep(Frontiers Media SA, 2022) Hitit, Mustafa; Köse, Mehmet; Kaya, Mehmet Salih; Kırbaş, Mesut; Dursun, Şükrü; Alak, İlyas; Atlı, Mehmet OsmanMicroRNA (miRNA) plays an important role in the control of gene expression and is implied in many biological functions, including embryo implantation and development. The aim was to assess plasma miRNA profiles during the peri-implantation and ascertain potential candidate miRNA markers for early pregnancy diagnosis in ovine plasma. The plasma samples were obtained from a total of 24 ewes on days 12 (pre-implantation; P12, n = 4), 16 (implantation; P16, n = 4) and 22 (post-implantation; P22, n = 4) after mating, and on their corresponding days of 12 (Pre-C; C12, n = 4), 16 (Imp-C; C16, n = 4) and 22 (Post-C; C22, n = 4) of the estrous cycle. The miRNA profiles in plasma were assessed by microarray technology. We detected the presence of 60 ovine-specific miRNAs in plasma samples. Of these miRNAs, 22 demonstrated a differential expression pattern, especially between the estrous cycle and early pregnancy, and targeted 521 genes. Two miRNAs (oar-miR-218a and oar-miR-1185-3p) were confirmed using RT-qPCR in the ovine plasma samples. Protein-protein interaction (PPI) network of target genes established six functional modules, of which modules 1 and 3 were enriched in the common GO terms, such as inflammatory response, defense response, and regulation of immune response. In contrast, module 2 was enriched in the developmental process involved in reproduction, embryo development, embryonic morphogenesis, and regulation of the developmental process. The results indicate that miRNAs profiles of plasma seemed to be modulated during the peri-implantation stage of pregnancy in ewes. Circulating miRNAs could be promising candidates for diagnosis in early ovine pregnancy.Öğe Oxidative stress in neonatal lambs and its relation to health status and passive colostral immunity(Elsevier, 2022) Gökce, Erhan; Cihan, Pınar; Atakişi, Onur; Kırmızıgül, Ali Haydar; Erdoğan, Hidayet MetinOxidative stress (OS) related to birth in ruminants may increase susceptibility to diseases. However, information about the physiological changes related to OS in lambs is limited. This study was designed to evaluate changes in OS parameters [total antioxidant status (TAS, mmol Trolox Equiv./L), total oxidant status (TOS, mu mol H2O2 Equiv./L)] and calculated oxidative stress index (OSi = TOS/TAS * 100, Arbitrary Unit) and its association with passive colostral transfer immunity and health status in neonatal Akkaraman crossbreed lambs. Control group of healthy lambs (n = 15) were blood sampled before (day 0) and after colostrum intake (on day 1, 2, 4, 7, 14 and 28) in order to evaluate the effect of colostrum intake on TAS, TOS and OSi over time. In addition, a group of lambs (experimental group, n = 60), based on their health status and different cut off value of IgG (mg/dL), was also blood sampled at 24 & PLUSMN; 1 h of colostrum ingestion to determine the relationship between OS parameters, IgG and health status. OS was evident at birth and gradually decreased in control group as TOS (days 0:8.06 & PLUSMN; 0.64, 1:7.05 +/- 0.51, 2:5.23 +/- 0.35, 4:5.05 & PLUSMN; 0.2, 7:5.13 v 0.34, 14:3.75 +/- 0.12 and 28:3.73 & PLUSMN; 0.15 mu mol H2O2 Equiv./L), OSi (days 0: 8.35 +/- 0.64, 1: 9.17 +/- 1.05, 2:6.83 +/- 0.6, 4:6.30 & PLUSMN; 0.20, 7:6.67 +/- 0.59, 14:4.46 & PLUSMN; 0.19 and 28:4.87 +/- 0.29 au) and TAS (days 0: 0.97 & PLUSMN; 0.02, 1:0.82 +/- 0.04, 2:0.81 +/- 0.05, 4:0.81 +/- 0.02, 7:0.80 +/- 0.03, 14:0.85 +/- 0.02 and 28:0.79 +/- 0.03 mmol Trolox Equiv./L) values changed over time. In the experimental group, the lambs died in the first week of the neonatal period had higher levels of TOS (10.3 +/- 0.90 mu mol H2O2 Equiv./L) and OSi (1.61 +/- 0.22 au) than healthy ones (TOS:6.90 +/- 0.36 mu mol HO2 Equiv./L, OSi:1.12 & PLUSMN; 0.11 au) (P < 0.001). The gradual decrease in OS in the neonatal period was accepted as a sign of improved antioxidant response. The study disclosed that deaths may develop when OS at birth is not balanced by sufficient amount and quality of colostrum an important source of antioxidants such as enzymes and vitamins. The study presented may provide new in-formation in the field of study on oxidative stress in neonatal lambs and help to prevent deaths in the first week of life. It can also be useful in developing preventive measures such as supplements of antioxidants to colostrum.Öğe Successful treatment of a urinary foreign body by cystotomy in a cat(Universidad de Córdoba, 2022) Boztok Özgermen, Başak; Avcı, NihanObjective. The aim of this study is to present the diagnosis and treatment methods of a cat with hematuria and strangury which was diagnosed with a foreign body within the urinary bladder. Materials and methods. A 1-year-old, mixed breed, neutered male cat was presented with pollakiuria and hematuria. The abdominal examination revealed a contractile and painful urinary bladder. Results. The abdominal ultrasonographic examination demonstrated a linear foreign body (urinary catheter) in the bladder lumen. A standard midline cystotomy was made and a 6 cm long urinary catheter was removed from the bladder. The cat recovered uneventfully. The presence of foreign bodies in the urinary bladder is rare in veterinary practice. Conclusions. Ultrasonographic examination of the urinary bladder gives valuable information on the foreign body-related cystitis in cats.Öğe The effect of different ram introducing procedures (protocol 66) on fertility parameters in Anatolian Merino ewes during breeding season(TÜBİTAK, 2022) Dursun, ŞükrüIn this study, different applications of ram introduction at the beginning of the breeding season were investigated in terms of their effects on some fertility parameters. The rams were introduced to the herd (Farm II), removed for 6 days, and reintroduced again in the experiment group, while the rams stayed within the herd (Farm I) all of the breeding season in the control group. In both farms, ewes were hand mated. These practices were performed in two consecutive breeding seasons of 2014 and 2015. In farm II, in the following 13 days of the reintroduction of rams, 83.4% and 83.7% of the ewes were mated in 2014 and 2015, respectively. In farm I, these ratios were 67.9% and 75.7%. In farm II, the breeding season lasted 18 and 28 days in 2014 and 2015, respectively, while it lasted 28 and 40 days in Farm I. In farm II, 77% of births occurred within 11 days in 2014 and 82% in 15 days in 2015, and the births were completed in 27 and 32 days, respectively. In farm I, 65% of births occurred within 14 days in 2014 and 74% in 17 days in 2015, and the births were completed in 41 and 43 days, respectively. Mating and birth periods were compared, and significant differences (P values?) were found between the farms. Although breeding and offspring parameters were not different, the parameters investigated had positive results for farm II. As a result, when rams are introduced for 6 days, removed for 6 days, and reintroduced into the flocks, the breeding and the birth periods might be shortened, however there is no benefit in terms of production.Öğe A Retrospective Comparison of Clinical and Radiological Outcomes of Plate Osteosynthesis in Cats with Ilial Body Fractures(Hellenic Veterinary Medical Society, 2022) Arıcan, M.; Zamirbekova, N.; Uzunlu, E.O.; Özdil, B.; Gümüş, F.elvic fractures are one of the most common orthopedic problems that cause serious injuries in cats, making up 20 to 32% of all feline fractures. Fractures of the ilium constitute 18 to 46% of pelvic fractures. In this study, the post-operative clinical and radiological results of dorsal, ventral and lateral aspects of the body of the ilium in cats with ilial fractures were evaluated. Twenty-three cats of different breeds, ages and sexes with ilial fractures and occasionally fractures of acetabular, ischial fractures and sacro-iliac joint luxation, were used as subject. History, clinical and neurological examinations of patients were undertaken, and three groups were formed for this study. Group 1 consisted of seven cases with the plate placed in the dorsal aspect of the ilium, group 2 consisted of seven cases with the plate placed on the lateral aspect of the ilium and in group 3, six cases had plates placed on the ventral aspect of the ilium. Surgery was performed under general anesthesia and either a Locking-Decompression Plate (LC-DCP) or a reconstruction plate was used for fixation. 85.7% with a full recovery rate of the cases. There was neither narrowing in the pelvic canal nor screw loosening in cases where the plate was applied dorsally and ventrally. In one case (14.3%), there was narrowing in the pelvic canal after lateral application. No difference was observed between the clinical and radiological results of placing LC-DCP or reconstruction plates on the dorsal, lateral, and ventral aspect of the bone in the post-operative period, and screw loosening did not occur. Case selection is important in the choice, when considering lateral, dorsal, or ventral plate application in ilial fractures. If the original injury was more than five to six days before surgery, double plate application provided a better clinical prognosis. Dorsal plate application provided better surgical access when compared to ventral application. Lateral application should be used if the fracture line is close to the acetabulum.Öğe Cardioprotective effects of fetai Icidney-derived mesencliymai stem ceiis on doxorubicin-induced cardiotoxicity in rats(Polskie Towarzystwo Nauk Weterynaryjnych, 2022) Yavuz, Orhan; Boztok Özgermen, Başak; Haydardedeoglu, Ali Evren; Dinçel, Güngör ÇağdaşCardiotoxicity is one of the most common side effects of doxorubicin (DOX), a chemotlierapy drug used in tlie treatment of many carcinomas. In recent years, stem-cell therapies have been successfully used to prevent cardiotoxicity. This study investigated the efficacy of intraperitoneally administered fetal kidney-derived mesenchymal stem cells (FKD-MSCs) in preventing DOX-induced cardiotoxicity in rats. For this purpose, thirty rats were randomly divided into three groups: control, DOX and mesenchymal stem cell (MSG) groups. Adriamycin was injected as a single dose via the tail vein in the DOX and MSG groups in order to induce cardiotoxicity. FKD-MSG was applied to the MSG group by the intraperitoneal route after cardiotoxicity had been established. Then the rats were euthanized, and routine histological procedures were performed on their hearts. H&E and Masson's stains were used for histopathology. Gardiac Troponin-T and I (cTnT, cTnl), Gaspase-3 and BGL-XL antibodies were used for immunohistochemistry. Vacuoles, edema, degeneration and necrosis were observed histopathologically mostly in the DOX group. Lesions in the control and MSG groups were less severe. Fibrosis in the control and MSG groups was milder. cTnT and cTnl immunopositive staining was most commonly seen in the control group, followed by the MSG group. Immunohistochemical staining by Gaspase-3 and BGL-XL showed that their expressions in the MSG group were statistically similar to those in the control group. Accordingly, it was concluded that the intraperitoneal application of MSG had a positive effect on histopathological findings, fibrosis, immunohistochemistry, especially apoptosis, neovascularization, and anti-apoptotic development, whereas troponin levels were not found to be therapeutic.
