Evaluation of fetal heart serum amyloid a concentrations in infectious cattle abortion cases

dc.contributor.authorAras, Zeki
dc.contributor.authorYavuz, Orhan
dc.date.accessioned2023-01-11T06:58:13Z
dc.date.available2023-01-11T06:58:13Z
dc.date.issued2022
dc.departmentVeteriner Fakültesi
dc.description.abstractSerum amyloid A (SAA) concentrations have been investigated in diseases of human and domestic animals and increased SAA levels have been reported in infectious diseases. In the present study, we determined the fetal heart blood SAA concentrations in aborted bovine fetuses and investigated the relationship between the level of SAA and causative infectious agents. A total of 46 heart blood samples were collected from aborted bovine fetuses between July 2018 and July 2019 and were assigned to two groups according to microbiological, pathological and molecular results. Group 1: An infectious disease was diagnosed by detecting a microorganism (21 cases); Group 2: An infectious or inflammatory disease was not detected (25 cases). The fetal heart blood SAA concentrations were measured by commercial ELISA test. Serum amyloid A concentrations in aborted bovine fetuses were elevated from 6.1 to ?40 mg/L in 17 of 21 cases in group 1. In group 2, SAA concentrations were less than 2.5 mg/L in 23 of 25 cases. This difference was statistically significant between group 1 and group 2. These findings suggest that SAA concentrations in fetal heart blood from bovine fetuses is potentially a novel marker for distinguishing between infectious and non-infectious bovine abortion cases.
dc.identifier.doi10.1016/j.heliyon.2022.e11330
dc.identifier.endpage-en_US
dc.identifier.issn2405-8440
dc.identifier.issue11en_US
dc.identifier.pmid36387522
dc.identifier.scopusqualityQ1
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/10.1016/j.heliyon.2022.e11330
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9868
dc.identifier.volume8en_US
dc.identifier.wosWOS:000905233500010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofHeliyon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAbortion
dc.subjectCattle
dc.subjectELISA
dc.subjectFetus
dc.subjectSerum amyloid A
dc.titleEvaluation of fetal heart serum amyloid a concentrations in infectious cattle abortion cases
dc.typeArticle

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