Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species

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dc.authoridZengin, Gokhan -- 0000-0001-6548-7823; CAKMAK, Yavuz Selim -- 0000-0001-8954-5485
dc.contributor.authorAktümsek, Abdurrahman
dc.contributor.authorZengin, Gökhan
dc.contributor.authorGüler, Gokalp Özmen
dc.contributor.authorÇakmak, Yavuz Selim
dc.contributor.authorDuran, Ahmet
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-29T19:26:16Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-29T19:26:16Z
dc.date.issued2013
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractThe methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var. pseudobehen, C pyrrhoblephara and C antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), beta-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's calorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C polypodiifolia var. pseudobehen. Methanolic extracts from C polypodiifolia var. pseudobehen and C antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. (C) 2013 Elsevier Ltd. All rights reserved.
dc.description.sponsorshipSelcuk University Scientific Research Foundation (BAP); [11401066]
dc.description.sponsorshipThis study was supported financially as a project (11401066). The authors thank Selcuk University Scientific Research Foundation (BAP) for providing financial support for this study. The authors also want to thank Dr. Harun Simsek for proofreading the present manuscript.
dc.identifier.doi10.1016/j.fct.2013.01.018
dc.identifier.endpage296en_US
dc.identifier.issn0278-6915
dc.identifier.pmid23357566
dc.identifier.scopusqualityQ1
dc.identifier.startpage290en_US
dc.identifier.urihttps://doi.org/10.1016/j.fct.2013.01.018
dc.identifier.urihttps://hdl.handle.net/20.500.12451/5515
dc.identifier.volume55en_US
dc.identifier.wosWOS:000317536900038
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPergamon-Elsevier Science Ltd
dc.relation.ispartofFood and Chemical Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectCentaurea
dc.subjectAntioxidant
dc.subjectPhenolics
dc.subjectAnticholinesterase Activity
dc.titleAntioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species
dc.typeArticle

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