Antioxidant potentials and anticholinesterase activities of methanolic and aqueous extracts of three endemic Centaurea L. species
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Date
2013
Journal Title
Journal ISSN
Volume Title
Publisher
Pergamon-Elsevier Science Ltd
Access Rights
info:eu-repo/semantics/embargoedAccess
Abstract
The methanol and aqueous extracts of three endemic Centaurea species (C. polypodiifolia var. pseudobehen, C pyrrhoblephara and C antalyense) were investigated for their antioxidant and cholinesterase inhibitory activities. The antioxidant activities of these extracts were evaluated by in vitro models including, phosphomolybdenum assay, free radical scavenging assays (DPPH and ABTS), beta-carotene/linoleic acid test system, metal chelating assay, FRAP assay, ferric and cupric reducing power. Cholinesterase inhibitory activities were examined using Ellman's calorimetric method. Total phenol, flavonoid, and saponin contents were also measured. Among the six Centaurea extracts evaluated, the highest antioxidant abilities were obtained from C polypodiifolia var. pseudobehen. Methanolic extracts from C polypodiifolia var. pseudobehen and C antalyense had a noticeable inhibition towards AChE and BChE. These findings suggest that Centaurea species could be an anticholinesterase agent and antioxidant resource in some industries, such as food, pharmacology, and cosmetics. (C) 2013 Elsevier Ltd. All rights reserved.
Description
Keywords
Centaurea, Antioxidant, Phenolics, Anticholinesterase Activity
Journal or Series
Food and Chemical Toxicology
WoS Q Value
N/A
Scopus Q Value
Q1
Volume
55
