Hematologic parameters as predictive markers in pediatric Bell's palsy

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dc.contributor.authorÇayır, Serkan
dc.contributor.authorKılıçaslan, Cengizhan
dc.date.accessioned2021-06-28T11:27:56Z
dc.date.available2021-06-28T11:27:56Z
dc.date.issued2020
dc.departmentTıp Fakültesi
dc.description.abstractPurpose To analyze various hematological parameters in pediatric population with Bell's palsy (BP) and to determine the most valuable parameter as a prognostic marker. Methods Fifty-nine patients with BP under 18 years were enrolled, and patients were divided into three groups: recovery group (49 cases), non-recovery group (10 cases) and controls (65 healthy children). Age, white blood cell (WBC), hemoglobin (Hbg), mean platelet volume (MPV), red cell distribution width (RDW), neutrophil-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and C-reactive protein-to-albumin ratio (CAR) were determined and compared between groups. Additionally, the receiver operating characteristics (ROC) analysis was carried out, and the most valuable marker to demonstrate the prognosis among these parameters was investigated. Results While mean age was found as 10.69 +/- 5.76 years, 28 (47.5%) female and 31 (52.5%) male pediatric patients were determined to be followed up due to BP in our hospital. When such parameters age, mean Hbg, MPV and RDW were examined, no significant difference was detected between groups. However, compared controls with recovery and non-recovery groups, WBC, NLR, PLR and CAR were found to be significantly higher, respectively (p < 0.05). Median CAR and NLR values were found to be significantly higher in non-recovery group, compared to those in recovery group (p = 0.001, p = 0.012, respectively). However, when median WBC and PLR were examined between recovery and non-recovery groups, no significant difference was observed (p > 0.05). Conclusion High NLR and CAR values in pediatric BP may be related to poor prognosis in such patients. CAR, however, is a more valuable parameter than NLR in terms of indicating poor prognosis.
dc.identifier.doi10.1007/s00405-020-06459-w
dc.identifier.endpage1269en_US
dc.identifier.issue4en_US
dc.identifier.pmid33159247
dc.identifier.scopusqualityQ1
dc.identifier.startpage1265en_US
dc.identifier.urihttps:/dx.doi.org/10.1007/s00405-020-06459-w
dc.identifier.urihttps://hdl.handle.net/20.500.12451/8207
dc.identifier.volume278en_US
dc.identifier.wosWOS:000587088700002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofEuropean Archives of Oto-Rhino-Laryngology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectPalsy
dc.subjectHematologic Parameters
dc.subjectPediatrics
dc.subjectPrognosis
dc.titleHematologic parameters as predictive markers in pediatric Bell's palsy
dc.typeArticle

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