Physicochemical and in vitro cytotoxic properties of chitosan from mushroom species (Boletus bovinus and Laccaria laccata)
| dc.contributor.author | Oberemko, Alona | |
| dc.contributor.author | Salaberria, Asier M. | |
| dc.contributor.author | Saule, Rita | |
| dc.contributor.author | Saulis, Gintautas | |
| dc.contributor.author | Kaya, Murat | |
| dc.contributor.author | Labidi, Jalel | |
| dc.date.accessioned | 2019-07-04T10:53:31Z | |
| dc.date.available | 2019-07-04T10:53:31Z | |
| dc.date.issued | 2019 | |
| dc.department | Sabire Yazıcı Fen Edebiyat Fakültesi | |
| dc.description | Kaya, Murat ( Aksaray, Yazar ) | |
| dc.description.abstract | Chitosan samples from two mushroom species (Boletus bovinus, Laccaria laccata) were obtained and characterized by viscosimetry, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), elemental analyses (EA), nuclear magnetic resonance spectroscopy (13C NMR), X-ray diffraction (XRD) and thermogravimetric (TGA) analyses. Properties of the fungal chitosan samples were compared to commercial low-molecular weight chitosan, crustacean chitosan (Cervimunida johni) and chitosan obtained from an insect (Hilobius abietis). Additionally, the cytotoxic properties of chitosan in vitro on cancerous hepatoma and non-cancerous ovary cells cultivated on films with different chitosan concentrations was evaluated. As a conclusion, this study clearly revealed that low-molecular weight chitosan films and solutions with high degree of deacetylation can act cytotoxically on both tumor MH-22A and normal CHO cells in vitro. Consequently, this work may be useful for further investigations of natural anticancer products in medical areas. | |
| dc.description.abstract | ... | |
| dc.identifier.doi | 10.1016/j.carbpol.2019.05.073 | |
| dc.identifier.endpage | 9 | en_US |
| dc.identifier.scopusquality | N/A | |
| dc.identifier.startpage | 1 | en_US |
| dc.identifier.uri | https://dx.doi.org/10.1016/j.carbpol.2019.05.073 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/1844 | |
| dc.identifier.volume | 221 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Elsevier Ltd. | |
| dc.relation.ispartof | Journal of Elsevier | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Mushroom | |
| dc.subject | Chitosan | |
| dc.subject | Cancer | |
| dc.subject | Low-Molecular Weight | |
| dc.subject | Deacetylation | |
| dc.title | Physicochemical and in vitro cytotoxic properties of chitosan from mushroom species (Boletus bovinus and Laccaria laccata) | |
| dc.type | Article |
