Monocyte/High-Density lipoprotein ratio is an indicator of activity in patients with ulcerative colitis
| dc.authorid | 0000-0003-1054-1882 | |
| dc.authorid | 0000-0001-8137-0924 | |
| dc.authorid | 0000-0002-7288-3936 | |
| dc.authorid | 0000-0002-5706-2136 | |
| dc.contributor.author | Yalçın, Mehmet Suat | |
| dc.contributor.author | Yalaki, Serkan | |
| dc.contributor.author | Ölmez, Şehmus | |
| dc.contributor.author | Taş, Adnan | |
| dc.date.accessioned | 2022-07-26T08:07:02Z | |
| dc.date.available | 2022-07-26T08:07:02Z | |
| dc.date.issued | 2022 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | In patients with ulcerative colitis, endoscopic and clinical indices are used to assess the disease activity. In addition, stud- ies have been carried out for easier and cheaper markers in recent years. For this purpose, we evaluated the monocyte/high-density lipoprotein ratio of the disease activity. Methods: According to clinical activity and partial Mayo scores, a total of 114 patients, 53 in the active ulcerative colitis group and 61 in the ulcerative colitis remission group were included in the study. Monocyte/high-density lipoprotein ratio, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, C-reactive protein, and erythrocyte sedimentation rate measurements of these 2 groups were recorded. Ulcerative colitis remission group and active ulcerative colitis group were compared in terms of activity. Results: The monocyte/high-density lipoprotein ratio value in the active ulcerative colitis group was significantly higher than that of the ulcerative colitis remission group (10.68 ± 3.39, 6.68 ± 1.39, P < .001, respectively). The monocyte/high-density lipoprotein ratio value for active ulcerative colitis at a cut-off value of 7.4 had 83% sensitivity and 81% specificity. In the active ulcerative colitis group, neutrophil/lymphocyte ratio, C-reactive protein, and erythrocyte sedimentation rate values were significantly higher than the ulcerative colitis remission group (P < .001, P < .001, P < .001, respectively). Conclusion: Monocyte/high-density lipoprotein ratio is an inexpensive and effective marker that can be used to determine the activity of ulcerative colitis. | |
| dc.identifier.doi | 10.5152/tjg.2022.214 | |
| dc.identifier.endpage | 335 | en_US |
| dc.identifier.issue | 4 | en_US |
| dc.identifier.scopusquality | N/A | |
| dc.identifier.startpage | 329 | en_US |
| dc.identifier.uri | https://dx.doi.org/10.5152/tjg.2022.214 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/9607 | |
| dc.identifier.volume | 33 | en_US |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Türk Gastroenternoloji Derneği | |
| dc.relation.ispartof | Türk Gastroenteroloji Derneği | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | C-reactive Protein | |
| dc.subject | Monocyte/HDL Ratio | |
| dc.subject | Neutrophil/lymphocyte Ratio | |
| dc.subject | Ulcerative Colitis | |
| dc.title | Monocyte/High-Density lipoprotein ratio is an indicator of activity in patients with ulcerative colitis | |
| dc.type | Article |
