Dynamic changes in aortic stiffness after substantial weight loss by laparoscopic sleeve gastrectomy in patients with obesity: A 1-year follow-up study

dc.authorid0000-0002-4576-128X
dc.contributor.authorGül, Murat
dc.contributor.authorİnci, Sinan
dc.contributor.authorAktaş, Halil
dc.contributor.authorYıldırım, Oğuz
dc.contributor.authorAlsancak, Yakup
dc.contributor.authorÖzkan, Namık
dc.date.accessioned2021-07-06T08:26:26Z
dc.date.available2021-07-06T08:26:26Z
dc.date.issued2021
dc.departmentTıp Fakültesi
dc.description*Gül, Murat ( Aksaray, Yazar ) *İnci, Sinan ( Aksaray, Yazar )
dc.description.abstractArterial stiffness has been identified as a powerful and independent risk factor for cardiovascular disease. Obesity is associated with an increased risk of aortic stiffness (AS) and adverse cardiovascular events. Herein, we aimed to evaluate the effects of weight loss after laparoscopic sleeve gastrectomy (LSG) on AS in individuals with morbid obesity by using the transthoracic echocardiography (TTE). A total of 53 patients with obesity (17 males, 36 females) who underwent LSG and did not have any known heart disease were included in the study. The AS parameters were measured with TTE. The demographic and echocardiographic data of the patients were studied before, at 1 month and 12 months after surgery. The mean age of the study group was 34.41±11.62, 68% of whom were female. There were no significant differences in terms of the standard echocardiography and Doppler measurements as compared with preoperative values (all p>0.05). When the elastic parameters of the aorta were compared, no significant differences were detected regarding aortic strain (%) ((16.28±4.11) vs (16.68±4.56), p=(0.998)), distensibility (cm2/dyn) ((6.74±1.78) vs (7.03±2.31), p=(0.997)) and Aortic Stiffness Index values ((10.73±3.84) vs (10.63±3.34), p=0.998) between baseline and first month after surgery. In the 12-month follow-up, it was determined that the aortic strain ((16.28±4.11) vs (22.74±5.79), p?0.001) and distensibility ((6.74±1.78) vs (10.34±3.059), p<0.001)) values increased at significant levels. Weight loss by LSG improves arterial stiffness parameters in patients with obesity over a 1-year follow-up.
dc.identifier.doi10.1136/jim-2021-001778
dc.identifier.endpage-en_US
dc.identifier.issn1081-5589
dc.identifier.issue-en_US
dc.identifier.pmid33771842
dc.identifier.scopusqualityQ2
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/10.1136/jim-2021-001778
dc.identifier.urihttps://hdl.handle.net/20.500.12451/8336
dc.identifier.volume-en_US
dc.identifier.wosWOS:000680407000006
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBMJ Publishing Group
dc.relation.ispartofJournal of Investigative Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGastrectomy
dc.subjectObesity
dc.subjectVascular Stiffness
dc.titleDynamic changes in aortic stiffness after substantial weight loss by laparoscopic sleeve gastrectomy in patients with obesity: A 1-year follow-up study
dc.typeArticle

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