Effect of quadrant switch on intraocular pressure change in intravitreal aflibercept or ranibizumab injection applications

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dc.authorid0000-0002-0422-1586
dc.authorid0000-0003-4468-3985
dc.authorid0000-0003-2544-3580
dc.contributor.authorAltıntaş, Melek
dc.contributor.authorUlaş, Fatih
dc.contributor.authorÇelebi, Serdal
dc.contributor.authorUyar, Enes
dc.date.accessioned2022-05-17T05:47:20Z
dc.date.available2022-05-17T05:47:20Z
dc.date.issued2022
dc.departmentTıp Fakültesi
dc.description.abstractTo evaluate the effect of injection quadrant switch on the intraocular pressure (IOP) change in intravitreal aflibercept or ranibizumab applications. Methods: 123 eyes of 123 patients who received intravitreal injection (IVE) into the superotemporal quadrant at least 10 times for age-related macular degeneration or diabetic macular edema have been recruited. The demographic data, lens status, IOP values (preoperative, postoperative 0th min, and postoperative 30th min), and amount of vitreous reflux (VR) following IVE have been recorded. Next IVE application was performed into the inferotemporal quadrant of the patient, which had never been injected before. Results: The mean IOP value at postoperative 0th min was 50.24 ± 7.66 mmHg after injections into the superotemporal quadrant and was 34.85 ± 4.96 mmHg after injections into the inferotemporal quadrant. No significant difference was observed between the preoperative and postoperative 30th min-IOP values (p > 0.05), while a significant difference was found between the postoperative 0th min-IOP values among quadrants (p < 0.001). VR was significantly higher in applications into the inferotemporal quadrant than those into the superotemporal quadrant (p < 0.001). Conclusion: One of the most principal factors affecting the postoperative short-term IOP increase is the amount of VR, and this amount decreases the IOP following an IVE.
dc.identifier.endpage-en_US
dc.identifier.issn0165-5701
dc.identifier.issue-en_US
dc.identifier.pmid35357637
dc.identifier.scopusqualityQ2
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/International Ophthalmology
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9394
dc.identifier.volume-en_US
dc.identifier.wosWOS:000782219600003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Science and Business Media B.V.
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectAflibercept
dc.subjectIntraocular Pressure
dc.subjectIntravitreal Injection
dc.subjectQuadrant Switch
dc.subjectRanibizumab
dc.subjectVitreous Reflux
dc.titleEffect of quadrant switch on intraocular pressure change in intravitreal aflibercept or ranibizumab injection applications
dc.typeArticle

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