Navigation problems of ICSI or naive blastocyst can be solved with artificial blastocyst

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dc.authoridUnlu, Cihat -- 0000-0001-5507-3993
dc.contributor.authorÇelik, Önder
dc.contributor.authorAcet, Mustafa
dc.contributor.authorArpacı, Haldun
dc.contributor.authorDikbaş, Levent
dc.contributor.authorİmren, Aytaç
dc.contributor.authorDuran, Bülent
dc.contributor.authorÇelik, Nilüfer
dc.contributor.authorÇelik, Sudenaz
dc.contributor.authorÜnlü, Cihat
dc.contributor.authorŞahin, İbrahim
dc.contributor.authorAydın, Süleyman
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:17:14Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:17:14Z
dc.date.issued2018
dc.department[Celik, Onder] Private Clin, Obstet & Gynecol, Usak, Turkey -- [Acet, Mustafa] Private Clin, Obstet & Gynecol, Istanbul, Turkey -- [Arpaci, Haldun] Kafkas Univ, Dept Obstet & Gynecol, Sch Med, Kars, Turkey -- [Dikbas, Levent] Aksaray Univ, Dept Obstet & Gynecol, Sch Med, Aksaray, Turkey -- [Imren, Aytac] Med Pk Hosp, Dept Obstet & Gynecol, Usak, Turkey -- [Duran, Bulent] Adatip Private Hosp IVF Ctr, Kocaeli, Turkey -- [Celik, Nilufer] BehcetUz Childrens Hosp, Dept Biochem, Izmir, Turkey -- [Celik, Sudenaz] Kent Coll Guzelbahce High Sch, Izmir, Turkey -- [Unlu, Cihat] Acibadem Univ, Sch Med, Dept Obstet & Gynecol, Istanbul, Turkey -- [Sahin, Ibrahim] Erzincan Univ, Sch Med, Dept Med Biol, Erzincan, Turkey -- [Aydin, Suleyman] Firat Univ, Sch Med, Dept Med Biochem, Firat Hormones Res Grp, Elazig, Turkey
dc.description.abstractEmbryos have evolved a remarkable capacity to find implantation site. The impressive navigation ability of natural blastocysts may rely on highly sensitive signals arising from embryos and specialized signal processing strategies in the endometrium. Navigation capabilities may be compromised in ICSI embryos because of altered biochemical signaling. The design and delivery of artificial blastocyst (AB) carrying strong chemical signals may allow ICSI embryos to more easily locate to and be retained in the implantation zone. ICSI embryos will attach easily to the implantation zone after it is found by the AB. Co-transfer of the AB together with the ICSI embryo may overcome potential difficulties in implantation due to impaired embryo-maternal communication in cases with implantation failure.
dc.identifier.doi10.1186/s12958-018-0326-1
dc.identifier.issn1477-7827
dc.identifier.pmid29378656
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1186/s12958-018-0326-1
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4721
dc.identifier.volume16en_US
dc.identifier.wosWOS:000423835300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBioMed Central Ltd.
dc.relation.ispartofReproductive Biolgy and Endocrinology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleNavigation problems of ICSI or naive blastocyst can be solved with artificial blastocyst
dc.typeArticle

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