Structural characteristics of Lacticaseibacillus rhamnosus ACS5 exopolysaccharide in association with its antioxidant and antidiabetic activity in vitro
| dc.contributor.author | İnanan, Tulden | |
| dc.contributor.author | Önal Darılmaz, Derya | |
| dc.contributor.author | Karaduman Yeşildal, Tuğçe | |
| dc.contributor.author | Yavuz, Serkan | |
| dc.date.accessioned | 2024-11-13T11:43:38Z | |
| dc.date.available | 2024-11-13T11:43:38Z | |
| dc.date.issued | 2024 | |
| dc.department | Teknik Bilimler Meslek Yüksekokulu | |
| dc.description.abstract | A novel structure of exopolysaccharide from the Lactic Acid Bacteria (LAB) Lacticaseibacillus rhamnosus ACS5, isolated from home-made Turkish cheese, is described. After lyophilization, the L-EPS-ACS5 was characterized in production and functional activities in vitro, including antioxidant and antidiabetic activities. The physicochemical characterizations of the L-EPS-ACS5 were determined through molecular weight, UV, FTIR, SEM, TGA, HPLC, NMR, methylation, and GC–MS analysis. Strong antioxidant activities of L-EPS-ACS5 were confirmed from the results obtained in the hydroxyl radical, DPPH, ABTS, FRAP, superoxide anion radical, total antioxidant activity, and DNA damage protective effect, and also the L-EPS-ACS5 exhibited high antidiabetic activity (60 %). This study isolated L-EPS-ACS5 from a home-made cheese L. rhamnosus strain, demonstrating its novel and enhanced functionalities compared to existing strains. This opens exciting avenues for its development in the fields of biomedicine and pharmaceuticals. | |
| dc.identifier.doi | 10.1016/j.ijbiomac.2024.136148 | |
| dc.identifier.issn | 0141-8130 | |
| dc.identifier.issue | - | en_US |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.uri | https:/dx.doi.org/10.1016/j.ijbiomac.2024.136148 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/12623 | |
| dc.identifier.volume | 280 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | International Journal of Biological Macromolecules | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Lacticaseibacillus Rhamnosus | |
| dc.subject | Exopolysaccharide | |
| dc.subject | Characterization | |
| dc.subject | Antioxidant | |
| dc.subject | Antidiabetic | |
| dc.title | Structural characteristics of Lacticaseibacillus rhamnosus ACS5 exopolysaccharide in association with its antioxidant and antidiabetic activity in vitro | |
| dc.type | Article |
