Macroporous surgical mesh from a natural cocoon composite

dc.contributor.authorChen, Yong-Ming
dc.contributor.authorZang, Lian-Sheng
dc.contributor.authorKoç-Bilican, Behlül
dc.contributor.authorBilican, İsmail
dc.contributor.authorHolland, Chris
dc.contributor.authorCansaran-Duman, Demet
dc.contributor.authorKaraduman, Tuğçe
dc.contributor.authorÇolak, Arzu
dc.date.accessioned2022-06-21T05:40:44Z
dc.date.available2022-06-21T05:40:44Z
dc.date.issued2022
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractRecently, traditional polymer-based surgical meshes have drawn unwanted attention as a result of host tissue complications arising from infection, biocompatibility, and mechanical compatibility. Seeking an alternative solution, we present a hierarchically structured nanofibrous surgical mesh derived from the naturally woven cocoon of the Japanese giant silkworm, termed MothMesh. We report that it displays nontoxicity, biocompatibility, suitable mechanical properties, and porosity while showing no adverse effect in animal trials and even appears to enhance cell proliferation. Hence, we assert that the use of this natural material may provide an effective and improved alternative to existing synthetic meshes.
dc.identifier.doi10.1021/acssuschemeng.1c06941
dc.identifier.endpage-en_US
dc.identifier.issn2168-0485
dc.identifier.issue-en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/10.1021/acssuschemeng.1c06941
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9450
dc.identifier.volume-en_US
dc.identifier.wosWOS:000800521700004
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmerican Chemical Society
dc.relation.ispartofACS Sustainable Chemistry and Engineering
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - İdari Personel ve Öğrenci
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBiocompatibility
dc.subjectFibroin
dc.subjectSericin
dc.subjectSurgical Mesh
dc.subjectTissue Engineering
dc.subjectSustainable Material
dc.titleMacroporous surgical mesh from a natural cocoon composite
dc.typeArticle

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