Is neutrophil/eosinophil ratio at admission a prognostic marker for in-hospital mortality of acute ischemic stroke?
Yükleniyor...
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
W.B. Saunders
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objectives: There has been a recent focus on hematological parameters affecting the prognosis of acute ischemic stroke (AIS). However, there are no studies investigating the neutrophil/eosinophil ratio (NER). This study aimed to investigate whether NER at admission is a prognostic marker for in-hospital mortality in patients with AIS. Methods: 204 AIS patients with similar vascular occlusion were included in the study, including 135 patients who survived and 69 patients who died in the hospital. Multivariate logistic regression analysis was performed to investigate the prognostic factors of AIS. The receiver operating characteristics (ROC) curve analysis was used to evaluate the predictive value of the variables and calculate the cut-off values. Results: 69 patients died in the hospital [24 men and 45 women, median age: 78 (49-99)], and 135 patients survived [58 men and 77 women, median age: 74 (22–99)]. The mean age of patients with mortality was higher compared to the patients who survived (p value=0.007). Multivariate logistic regression model revealed that only NER and red blood cell distribution width (RDW-SD) were prognostic factors (p = 0.036 and p = 0.032, respectively). Areas under the ROC curve were 0.675 for NER (95% CI, 0.59–0.75), 0.636 for neutrophil (95% CI, 0.55–0.71), 0.602 for RDW-SD (95% CI, 0.51-0.69) and 0.656 for eosinophil (95% CI, 0.57-0.74). Conclusion: Our results showed that there is a correlation between the in-hospital mortality of AIS and high NER at admission. NER at admission can be used as a poor prognostic marker for AIS.
Açıklama
Anahtar Kelimeler
Acute Ischemic Stroke, Eosinophil, First Admission, Neutrophil/eosinophil Ratio, Red Blood Cell Distribution Width
Kaynak
Journal of Stroke and Cerebrovascular Diseases
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
29
Sayı
8
