Evaluation of 25-hydroxy vitamin D levels and disease severity in patients with acne vulgaris
| dc.contributor.author | Kemeriz, Funda | |
| dc.contributor.author | Tuncer, Sibel Çiğdem | |
| dc.contributor.author | Acar, Emine Müge | |
| dc.contributor.author | Tu?rul, Burcu | |
| dc.date.accessioned | 2020-06-10T12:34:04Z | |
| dc.date.available | 2020-06-10T12:34:04Z | |
| dc.date.issued | 2020 | |
| dc.department | Tıp Fakültesi | |
| dc.description | *Kemeriz, Funda( Aksaray, Yazar ) *Tuncer, Sibel Çiğdem( Aksaray, Yazar ) | |
| dc.description.abstract | Acne vulgaris is a multifactorial skin disorder. Many etiological factors are speculated to contribute to the pathogenesis of acne, one of these is vitamin D deficiency. Previous studies reported contradictory results about serum 25 hydroxy vitamin D (25-OH vitamin D) levels, its association with acne, some claimed that acne lesion might improve with vitamin D supplementation. We aimed to assess serum 25-OH vitamin D levels in acne patients, identify their relation with disease severity in a larger study group. The study included 134 acne patients, 129 controls. Acne disease severity was identified with Global Acne Grading Scale (GAGS) scores. Serum 25-OH vitamin D levels were measured in all groups. Serum 25-OH vitamin D levels were significantly lower in acne patients than in controls (P <.001). The prevalence of vitamin D deficiency was significantly higher in acne group than in control group (77.6% vs 63.9%; P =.041). There was a negative-strong statistically significant correlation detected between serum 25-OH vitamin D levels and GAGS scores in patient group (P <.001; r = ?.910). According to these results, we claim that evaluating serum 25-OH vitamin D levels in acne patients, vitamin D supplementation as a treatment option may be a consideration for further studies. | |
| dc.identifier.doi | 10.1111/dth.13393 | |
| dc.identifier.endpage | - | en_US |
| dc.identifier.issn | 1396-0296 | |
| dc.identifier.issue | - | en_US |
| dc.identifier.pmid | 32268447 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | - | en_US |
| dc.identifier.uri | https://dx.doi.org/10.1111/dth.13393 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/7573 | |
| dc.identifier.volume | - | en_US |
| dc.identifier.wos | WOS:000530633200001 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Blackwell Publishing Inc. | |
| dc.relation.ispartof | Dermatologic Therapy | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Acne | |
| dc.subject | Disease Severity | |
| dc.subject | Vitamin D | |
| dc.title | Evaluation of 25-hydroxy vitamin D levels and disease severity in patients with acne vulgaris | |
| dc.type | Article |
