The novel indicators of moderate to severe sleep apnea: fibrinogen to albumin ratio vs. CRP to albumin ratio
| dc.contributor.author | Hızlı, Ömer | |
| dc.contributor.author | Çayır, Serkan | |
| dc.contributor.author | Çoluk, Yonca | |
| dc.contributor.author | Kayabaşı, Serkan | |
| dc.contributor.author | Yıldırım, Güven | |
| dc.date.accessioned | 2020-06-10T11:29:50Z | |
| dc.date.available | 2020-06-10T11:29:50Z | |
| dc.date.issued | 2021 | |
| dc.department | Tıp Fakültesi | |
| dc.description | Çayır, Serkan ( Aksaray, Yazar ) | |
| dc.description.abstract | Purpose: This study aimed at investigating the association of severity of obstructive sleep apnea with the markers of inflammation as fibrinogen to albumin ratio and C-reactive protein to albumin ratio. Methods: We included 126 patients admitted to sleep disorders outpatient clinic. We constituted four groups by reference to the apnea–hypopnea index (mild-moderate-severe sleep apnea and control group). We investigated the difference of white blood cell, fibrinogen to albumin ratio, C-reactive protein to albumin ratio, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and hemoglobin among the groups. Results: Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and hemoglobin did not significantly differ among four groups (p = 0.39, p = 0.06, and p = 0.31, respectively). A significant difference of fibrinogen to albumin ratio and C-reactive protein to albumin ratio was evident among four groups (p < 0.001). Fibrinogen to albumin ratio and C-reactive protein to albumin ratio did not significantly differ between the mild sleep apnea and control groups (p = 0.65, and p = 0.85, respectively), but were significantly greater in moderate sleep apnea group compared with the control group (p < 0.001 and p = 0.001, respectively). Also, fibrinogen to albumin ratio and C-reactive protein to albumin ratio were significantly greater in the severe sleep apnea group compared with the control group (p < 0.001). Fibrinogen to albumin ratio and C-reactive protein to albumin ratio did not significantly differ between the severe sleep apnea and moderate sleep apnea groups (p = 0.49, and p = 0.58, respectively). Conclusion: Higher fibrinogen to albumin ratio and C-reactive protein to albumin ratio may be predictive of inflammation in patients with moderate-to-severe sleep apnea. | |
| dc.identifier.doi | 10.1007/s00405-019-05770-5 | |
| dc.identifier.endpage | - | en_US |
| dc.identifier.issn | 0937-4477 | |
| dc.identifier.issue | - | en_US |
| dc.identifier.pmid | 31919564 | |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | - | en_US |
| dc.identifier.uri | https://dx.doi.org/10.1007/s00405-019-05770-5 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/7571 | |
| dc.identifier.volume | - | en_US |
| dc.identifier.wos | WOS:000574137400001 | |
| dc.identifier.wosquality | Q2 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | Springer | |
| dc.relation.ispartof | European Archives of Oto-Rhino-Laryngology | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Sleep Apnea | |
| dc.subject | Fibrinogen | |
| dc.subject | C-reactive Protein | |
| dc.subject | Albumin | |
| dc.title | The novel indicators of moderate to severe sleep apnea: fibrinogen to albumin ratio vs. CRP to albumin ratio | |
| dc.type | Article |
