Keratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases

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dc.authorid0000-0001-6789-8474
dc.authorid0000-0003-1670-0709
dc.authorid0000-0001-7039-8956
dc.authorid0000-0003-1943-2690
dc.contributor.authorAvcı, Nihan
dc.contributor.authorGümüş, Fehmiye
dc.contributor.authorBoztok Özgermen, Başak
dc.contributor.authorÖzen, Doğukan
dc.date.accessioned2025-04-09T06:18:52Z
dc.date.available2025-04-09T06:18:52Z
dc.date.issued2024
dc.departmentVeteriner Fakültesi
dc.description.abstractKeratoconjunctivitis sicca (KCS) is characterized by decreased aqueous tear film components, leading to ocular surface damage. Diagnosis involves clinical examination, Schirmer Tear Test (STT1), and Tear Film Break-Up Time (TFBUT) measurement. This retrospective study aimed to assess dry eye syndrome in intact, purebred, Aksaray Malakli breed dogs, and investigate potential associations with hereditary ocular diseases due to inbreeding for phenotype preservation. Animals: Fifty healthy, purebred, intact Aksaray Malakli dogs of varying ages and sexes, all exhibiting conjunctival hyperemia and mucoid ocular discharge. Dogs with chronic diseases, systemic medication, or ongoing ophthalmic treatment were excluded. Procedures: Demographic data, ophthalmic examination results, and ocular anomalies were recorded. STT1 and TFBUT assessments were performed to measure tear production and film stability. STT1 values were scored from 1 (normal) to 4 (severe dry eye), and TFBUT ≥20 s was considered normal. Statistical analyses were used to evaluate correlations and differences. Results: The correlation between age and STT1 values (r = −.182, p =.206) was not statistically significant. Mean STT1 was higher in females than males, though not significantly (p =.849). Dogs without third eyelid gland prolapse had significantly higher STT1 and TFBUT measurements compared to those with prolapse (p =.027). No significant sex difference was found in the frequency of third eyelid prolapse (p =.289). A significant positive correlation was observed between STT1 and TFBUT (r =.924; p <.001). Conclusions: Aksaray Malakli dogs, particularly those with third eyelid gland prolapse, are predisposed to mild to moderate KCS. These findings suggest the need for further clinical and genetic investigations to better understand and manage dry eye syndrome in this breed.
dc.identifier.doi10.1111/vop.13298
dc.identifier.issn14635216
dc.identifier.scopus2-s2.0-85211455010
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://dx.doi.org/10.1111/vop.13298
dc.identifier.urihttps://hdl.handle.net/20.500.12451/12988
dc.identifier.wos001374204000001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAvcı, Nihan
dc.institutionauthorGümüş, Fehmiye
dc.institutionauthorid0000-0001-6789-8474
dc.institutionauthorid0000-0003-1670-0709
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.relation.ispartofVeterinary Ophthalmology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCanine Ocular Disease
dc.subjectDiagnostic Tool
dc.subjectDry Eye
dc.subjectSchirmer Tear Test
dc.subjectTear Film
dc.subjectTear Film Break-up Time
dc.titleKeratoconjunctivitis sicca in intact Aksaray Malakli breed dogs: Evaluation of 50 cases
dc.typeArticle

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