Lactobacillus fermentum strains from human breast milk with probiotic properties and cholesterol-lowering effects

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dc.authoridAsan Ozusaglam, Meltem -- 0000-0002-3638-1306
dc.contributor.authorAşan-Özüsağlam, Meltem
dc.contributor.authorGünyaktı, Ayşe
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:15:09Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:15:09Z
dc.date.issued2019
dc.departmentFen-Edebiyat Fakültesi
dc.description.abstractThe study aimed to identify two lactic acid bacteria from human breast milk and evaluate for their probiotic potential. Lactobacillus fermentum strains showed various degree of antibiotic susceptibility profile to clinical commercial antibiotics. The MA-7 and MA-8 strains have never lost their vitality at pH 2 and 3. Lactobacillus fermentum MA-8 exhibited more resistance to 0.3 and 1% bile concentrations than MA-7 strain. Both of the L. fermentum strains can tolerate the simulated gastric and intestinal juices. The strains showed high auto-aggregation percentages varied from 95 to 98%. Both isolates also exhibited gamma hemolytic activity. The cholesterol lowering activity of MA-7 and MA-8 strains was varied from 34.84 to 91.15%. The supernatants showed higher anti-cholesterol activity compared to pellets. The results demonstrated that both L. fermentum strains maybe good probiotic candidates and may have potential as health biotherapeutic with cholesterol-lowering effects.
dc.description.sponsorshipScientific Research Projects Coordinator of Aksaray University-Turkey [2017/031]
dc.description.sponsorshipThis work was financially supported by The Scientific Research Projects Coordinator of Aksaray University-Turkey (Project number 2017/031).
dc.identifier.doi10.1007/s10068-018-0494-y
dc.identifier.endpage509en_US
dc.identifier.issn1226-7708
dc.identifier.issn2092-6456
dc.identifier.issue2en_US
dc.identifier.pmid30956862
dc.identifier.scopusqualityQ2
dc.identifier.startpage501en_US
dc.identifier.urihttps://doi.org/10.1007/s10068-018-0494-y
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4304
dc.identifier.volume28en_US
dc.identifier.wosWOS:000462163300022
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
dc.relation.ispartofFOOD SCIENCE AND BIOTECHNOLOGY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcid and Bile Tolerance
dc.subjectAntibiotic Susceptibility
dc.subjectAnti-Cholesterol
dc.subjectAuto-Aggregation
dc.subjectTransit Tolerance
dc.titleLactobacillus fermentum strains from human breast milk with probiotic properties and cholesterol-lowering effects
dc.typeArticle

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