Does iron therapy have a place in the management of all breath-holding spells?
| dc.contributor.author | Arslan, Müjgan | |
| dc.contributor.author | Karaibrahimoğlu, Adnan | |
| dc.contributor.author | Demirtaş, Mehmet Semih | |
| dc.date.accessioned | 2022-01-24T10:52:42Z | |
| dc.date.available | 2022-01-24T10:52:42Z | |
| dc.date.issued | 2021 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | Aim of this study was to analyze the effect of iron therapy in children with breath-holding spells, irrespective of their hemoglobin level. Method: All of the children were evaluated in terms of age, sex, age at onset of the attack, attack frequency, type of breath-holding spell, family pedigree, laboratory values. All enrolled patients were given iron at the dose of 4 mg/kg/day as a single daily dose for 3 months. Patients were called for follow-up appointments 1 and 3 months after the initiation of treatment to record the frequency and severity of spells. Results: The mean age of the patients was 12.50 ± 9.51 months. Patients were divided into two groups according to the hemoglobin level. The frequency of anemia in children with spells was recorded as 27%. Out of 100 patients treated with iron, 43% showed complete remission at the end of 1 month. At the end of the 3 months, percentage of complete responders increased to 80%. After three-month of iron treatment, 96.2% of the anemic and 73.97% of the non-anemic patients were spell-free. Eight children had mild adverse effects after iron therapy that did not require dose modification. Conclusions: This study confirmed that iron therapy reduces spell frequency regardless of anemia in all breath-holding spells. A three-month empiric iron therapy should be offered to all children with spells. | |
| dc.identifier.doi | 10.1111/ped.14685 | |
| dc.identifier.endpage | 1350 | en_US |
| dc.identifier.issn | 1328-8067 | |
| dc.identifier.issue | 11 | en_US |
| dc.identifier.pmid | 33682275 | |
| dc.identifier.scopusquality | Q3 | |
| dc.identifier.startpage | 1344 | en_US |
| dc.identifier.uri | https:/dx.doi.org/10.1111/ped.14685 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/9150 | |
| dc.identifier.volume | 63 | en_US |
| dc.identifier.wos | WOS:000711878000001 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | John Wiley and Sons Inc | |
| dc.relation.ispartof | Pediatrics International | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Breath-holding Spell | |
| dc.subject | Children | |
| dc.subject | Empiric Iron Therapy | |
| dc.title | Does iron therapy have a place in the management of all breath-holding spells? | |
| dc.type | Article |
