Increased epicardial adipose tissue thickness is associated with angiographic thrombus burden in the patients with non-ST-segment elevation myocardial infarction
Yükleniyor...
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SAGE Publications Inc.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We aimed to evaluate the relation among epicardial adipose tissue (EAT) thickness, angiographic presence of thrombus, and the no-reflow in the patients with non-ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The study population consisted of 229 patients. The EAT thickness and neutrophil to lymphocyte ratio (NLR) were significantly higher in the patients with coronary thrombus than in those without coronary thrombus (6.1 ± 1.1 vs 5.1 ± 1.3 mm, P <.001 and 3.4 ± 0.9 vs 2.5 ± 0.7, P <.001, respectively) and in the patients with no-reflow compared to patients with reflow. The EAT thickness was found to be correlated positively with the degree of the thrombus burden, NLR, and waist circumference and negatively with high-density lipoprotein cholesterol. Multivariate logistic regression analysis demonstrated that EAT thickness and NLR independently predicted coronary thrombus formation and no-reflow. We have suggested that EAT can play an important role in the pathophysiology of coronary thrombus formation and the no-reflow. © SAGE Publications.
Açıklama
PubMed ID: 25381157
Anahtar Kelimeler
Coronary Thrombus, Epicardial Adipose Tissue, No-reflow, Non-ST-segment Elevation Myocardial Infarction, Percutaneous Coronary Intervention
Kaynak
Clinical and Applied Thrombosis/Hemostasis
WoS Q Değeri
Scopus Q Değeri
Q2
Cilt
21
Sayı
7