Comparison of urine culture and complete urinalysis results in female patients with suspected urinary tract infection
dc.contributor.author | Kalaycı, Hacer Özlem | |
dc.contributor.author | Gürpınar, Ahmet Burak | |
dc.contributor.author | Erdal, Hüseyin | |
dc.date.accessioned | 2025-04-16T05:40:05Z | |
dc.date.available | 2025-04-16T05:40:05Z | |
dc.date.issued | 2024 | |
dc.department | Tıp Fakültesi | |
dc.description.abstract | Aim: This study aims to assess the effectiveness of fully automated urine tests by using urine culture results from female patients with suspected urinary tract infections as the reference standard and to determine their practicality for clinicians. Material and Methods: Chemical and microscopic analysis of urine was performed using a fully automatic urine analyzer (Roche Cobas 6500 u601-u701, Roche Diagnostics GmbH, Mannheim, Germany) in patients with a preliminary diagnosis of symptomatic urinary tract infection who were admitted to xxx University Training and Research Hospital gynecology outpatient clinic between January 2023 and January 2024. Midstream urine samples sent in sterile containers were inoculated on 5% sheep blood agar and EMB agar with a 0.001 caliber core and incubated at 37°C for 18-24 hours under aerop conditions. According to complete urinalysis, leukocyte count ≥5 and bacterial count ≥1 were considered positive, leukocyte esterase positivity and nitrite positivity were considered positive. Results: Escherichia coli (E.coli), Streptococcus agalactiae, Klebsiella pneumoniae, Staphylococcus sapropyticus and Candida spp. were most frequently isolated from a total of 295 urine cultures. The most effective antibiotics against the isolated E.coli strains were nitrofurantoin, fosfomycin, imipenem, meropenem and amikacin. When culture results were taken as gold standard, the diagnostic sensitivity, specificity and accuracy rates of leukocyte esterase and nitrite positivity were 78.3%, 44%, 52.1%, 24.1%, 99.9%, 82.1% for leukocyte esterase and nitrite, respectively. Discussion: We think that nitrite positivity may be a guide for unnecessary urine culture requests, but urinalysis parameters should not be used instead of culture due to their low accuracy rates. | |
dc.identifier.doi | 10.4328/ACAM.22349 | |
dc.identifier.endpage | 875 | |
dc.identifier.issue | 12 | |
dc.identifier.startpage | 871 | |
dc.identifier.uri | https://dx.doi.org/10.4328/ACAM.22349 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12451/13052 | |
dc.identifier.volume | 15 | |
dc.identifier.wos | 001424161100012 | |
dc.identifier.wosquality | Q4 | |
dc.indekslendigikaynak | Web of Science | |
dc.institutionauthor | Erdal, Hüseyin | |
dc.language.iso | en | |
dc.publisher | Bayrakol MP | |
dc.relation.ispartof | Annals of Clinical and Analytical Medicine | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.title | Comparison of urine culture and complete urinalysis results in female patients with suspected urinary tract infection | |
dc.type | Article |