Comparison of urine culture and complete urinalysis results in female patients with suspected urinary tract infection
Yükleniyor...
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bayrakol MP
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: This study aims to assess the effectiveness of fully automated urine tests by using urine culture results from female patients with suspected urinary tract
infections as the reference standard and to determine their practicality for clinicians.
Material and Methods: Chemical and microscopic analysis of urine was performed using a fully automatic urine analyzer (Roche Cobas 6500 u601-u701, Roche
Diagnostics GmbH, Mannheim, Germany) in patients with a preliminary diagnosis of symptomatic urinary tract infection who were admitted to xxx University
Training and Research Hospital gynecology outpatient clinic between January 2023 and January 2024. Midstream urine samples sent in sterile containers
were inoculated on 5% sheep blood agar and EMB agar with a 0.001 caliber core and incubated at 37°C for 18-24 hours under aerop conditions. According to
complete urinalysis, leukocyte count ≥5 and bacterial count ≥1 were considered positive, leukocyte esterase positivity and nitrite positivity were considered
positive.
Results: Escherichia coli (E.coli), Streptococcus agalactiae, Klebsiella pneumoniae, Staphylococcus sapropyticus and Candida spp. were most frequently isolated
from a total of 295 urine cultures. The most effective antibiotics against the isolated E.coli strains were nitrofurantoin, fosfomycin, imipenem, meropenem and
amikacin. When culture results were taken as gold standard, the diagnostic sensitivity, specificity and accuracy rates of leukocyte esterase and nitrite positivity
were 78.3%, 44%, 52.1%, 24.1%, 99.9%, 82.1% for leukocyte esterase and nitrite, respectively.
Discussion: We think that nitrite positivity may be a guide for unnecessary urine culture requests, but urinalysis parameters should not be used instead of
culture due to their low accuracy rates.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Clinical and Analytical Medicine
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
15
Sayı
12
