Prognostic value of high sensitive troponin T in patients with chronic ischemic heart disease undergoing percutaneous coronary intervention

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dc.contributor.authorAktaş, Halil
dc.contributor.authorKaypaklı, Onur
dc.contributor.authorÖzmen, Çağlar
dc.contributor.authorGül, Murat
dc.contributor.authorYıldırım, Oğuz
dc.contributor.authorİnci, Sinan
dc.contributor.authorDeniz, Ali
dc.contributor.authorDemirtaş, Mustafa
dc.date.accessioned2021-05-25T07:32:54Z
dc.date.available2021-05-25T07:32:54Z
dc.date.issued2021
dc.departmentTıp Fakültesi
dc.descriptionAktaş, Halil ( Aksaray, Yazar )
dc.description.abstractObjective: Several studies have investigated different cardiac biomarkers as predictors of the prognosis after percutaneous coronary interventions (PCI) in patients with chronic ischemic heart disease; nevertheless, the results of these studies are conflicting. High sensitive troponin T (Hs-TnT) measurement is a novel and sensitive method. The aim of this study was to investigate if Hs-TnT levels are a predictor of major adverse cardiovascular events (MACE) in the first year after a successful elective PCI in patients with stable angina pectoris (SAP). Material and methods: 100 patients who presented with SAP and underwent successfully elective PCI were included in the study. Patients with elevated troponin I levels (>0.1 ng/mL) before the procedure excluded from the study. Hs-TnT levels were measured before the procedure and at 3-4 hours (h) (early period) and 12-24 hours (late period) after the procedure and Hs-TnT level >14 pg/mL was considered positive. The incidence of MACE during the first year was recorded. Results: Hs-TnT levels were positive in 36% of the patients in the early period and in 54% of the patients in the late period. The incidence rate of MACE for the first year was significantly higher in the patients with positive Hs-TnT levels in the early period but not the late period (36.1% vs. 15.6%; p = 0.026) and logistic regression analysis yielded an odds ratio of 3.36. Conclusion: Hs-TnT levels measured 3-4 h after a successful elective PCI in patients with SAP can predict the incidence of MACE within the first year. Nonetheless, these results must be corroborated by other larger studies.
dc.identifier.doi10.33678/coL2020.082
dc.identifier.endpage39en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage32en_US
dc.identifier.urihttps:/dx.doi.org/10.33678/coL2020.082
dc.identifier.urihttps://hdl.handle.net/20.500.12451/7965
dc.identifier.volume63en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCzech Society of Cardiology - European Society of Cardiology
dc.relation.ispartofCor et Vasa |
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChronic Ischemic Heart Disease
dc.subjectHigh Sensitive Troponin T
dc.subjectMajor Adverse Cardiovascular Events
dc.subjectPercutaneous Coronary Intervention
dc.subjectPrognosis
dc.titlePrognostic value of high sensitive troponin T in patients with chronic ischemic heart disease undergoing percutaneous coronary intervention
dc.typeArticle

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