Predictors of acute kidney injury in chronic kidney disease patients treated for cardiovascular disease in the cardiac intensive care unit (MORCOR-TURK subgroup analysis)

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dc.authorid0000-0003-2279-6110
dc.contributor.authorDoğan, Ömer
dc.contributor.authorTaşdelen Acar, Aybüke Gül
dc.contributor.authorGül, Mural
dc.contributor.authorŞafak, Özgen
dc.contributor.authorÖmur, Sefa Erdi
dc.contributor.authorAtıcı, Adem
dc.contributor.authorBarman, Hasan Ali
dc.contributor.authorCengil, Muhammed Erkam
dc.contributor.authorYılmaz, Ahmet Şeyda
dc.contributor.authorErsoy, İbrahim
dc.date.accessioned2024-11-19T12:25:11Z
dc.date.available2024-11-19T12:25:11Z
dc.date.issued2024
dc.departmentTıp Fakültesi
dc.description.abstractBackground: Acute kidney injury (AKI) is a common complication in chronic kidney disease (CKD) patients in the cardiac intensive care unit (cardiac ICU). In this study, we aimed to identify predictors of AKI in CKD patients treated in the cardiac ICU for cardiovascular diseases. Methods: The MORCOR-TURK trial was conducted as a multicenter, prospective, cross-sectional, and noninterventional investigation. A total of 3157 patients treated in the cardiac ICU were enrolled from 50 centers over the course of one month. In this subgroup analysis, 615 patients with CKD treated in the cardiac ICU for cardiovascular disease were included in the study. The primary outcome of this study was the development of AKI. During hospitalization, patients who developed AKI were identified. Results: AKI developed in 288 patients (46%). After multivariable analysis, decompensated heart failure (OR: 3.72, p = 0.005), primary percutaneous coronary intervention (OR: 3.75, p = 0.004), non-primary percutaneous coronary intervention (OR: 2.85, p = 0.033), troponin levels (OR: 1.04, p = 0.031), and need for mechanical ventilation (OR: 3.11, p < 0.001) were identified as independent predictors of AKI development in CKD patients. Conclusion: Our efforts to identify AKI predictors in cardiac ICU patients with CKD have yielded directly applicable results in clinical practice. AKI can be prevented by developing personalized strategies to follow up and treat cardiac ICU patients with CKD who have decompensated heart failure, are undergoing percutaneous coronary intervention (primary and non-primary), have high troponin levels, and need mechanical ventilation.
dc.identifier.doi10.1007/s40620-024-02127-y.
dc.identifier.scopusqualityQ1
dc.identifier.urihttps:/dx.doi.org/10.1007/s40620-024-02127-y.
dc.identifier.urihttps://hdl.handle.net/20.500.12451/12656
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofJournal of Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAcute Kidney Injury
dc.subjectChronic Kidney Disease
dc.subjectCoronary Intensive Care Unit
dc.subjectClinical Predictors
dc.titlePredictors of acute kidney injury in chronic kidney disease patients treated for cardiovascular disease in the cardiac intensive care unit (MORCOR-TURK subgroup analysis)
dc.typeArticle

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