Free vitamin D and vitamin D binding protein in multiple sclerosis patients
| dc.contributor.author | Dönmez, Recep | |
| dc.contributor.author | Yıldız, Özlem Kayım | |
| dc.contributor.author | Görgülü, Ümit | |
| dc.date.accessioned | 2024-04-19T10:48:54Z | |
| dc.date.available | 2024-04-19T10:48:54Z | |
| dc.date.issued | 2023 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | In multiple sclerosis (MS), where low vitamin D level is a risk factor, there is no previous study evaluating the level of free vitamin D by direct measurement, and there is little information about vitamin D binding protein (DBP). This study assessed free vitamin D and DBP in patients with MS. Methods: The study subjects consisted of 43 MS patients and 25 controls. Free vitamin D and DBP levels were measured through an enzyme-linked immunosorbent (ELISA) kit. Results: The patient group had a mean age of 36.58 ± 9.4 (19-60) and the control group had a mean age of 33.56 ± 9.65 (24-52) years (p=0.210). The patient had free vitamin D level of 21.51 ±9.72 pg/ml and the free vitamin D level of the control group was 26.02 ±9.29 pg/ml. Free vitamin D levels did not significantly differ across the groups (p=0.065). The patient group (34.78 ±18.24 ng/ml) had a significantly higher DBP level than the control group (15.36 ±10.64 ng/ml) (p<0.001). Conclusion: MS patients have higher DBP than healthy control, while the free vitamin D levels of the patients tend to be lower. | |
| dc.identifier.doi | 10.54029/2023hhe | |
| dc.identifier.endpage | 686 | en_US |
| dc.identifier.issn | 1823-6138 | |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.startpage | 683 | en_US |
| dc.identifier.uri | https:/dx.doi.org10.54029/2023hhe | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/11659 | |
| dc.identifier.volume | 28 | en_US |
| dc.identifier.wos | WOS:001085393800023 | |
| dc.identifier.wosquality | Q4 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | ASEAN Neurological Association | |
| dc.relation.ispartof | Neurology Asia | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Free Vitamin D | |
| dc.subject | Multiple Sclerosis | |
| dc.subject | Vitamin D | |
| dc.subject | Vitamin D Binding Protein | |
| dc.title | Free vitamin D and vitamin D binding protein in multiple sclerosis patients | |
| dc.type | Article |
