Prognostic importance of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in patients with acute pulmonary embolism
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Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Czech Society of Cardiology Z.S
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
To investigate the prognostic value of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in acute pulmonary embolism (APE). Methods: We retrospectively evaluated patients aged 18 years and over who were diagnosed with APE by computed tomography pulmonary angiography at the emergency department (ED) between January 2019 and January 2023. The patients' clinical and demographic data were evaluated, and their simplifi ed pulmonary embolism severity index values were calculated. The HALP score was obtained using the fi rst blood sample measured after the patients were admitted to the ED. The HALP score was calculated according to the formula: HALP = hemoglobin × albumin × lymphocytes / platelets Results: The in-hospital mortality rate was 19.1% in 277 patients with APE included in the study. The HALP score of the patients who died was signifi cantly lower than the HALP score of those who survived (p <0.001). The cut-off value of the HALP score on the receiver operating characteristic (ROC) curve for in-hospital mortality was 3.21 (sensitivity: 81.13%; specifi city: 84.37%; area under the ROC curve [AUC]: 0.879, 95% confi dence interval [CI]: 0.827-0.930, p <0.001). A logistic regression analysis was performed based on these cut-off values, and the multivariate logistic regression analysis revealed that the HALP score (odds ratio: 0.24, 95% CI: 0.17-0.96) was an independent indicator of mortality. Conclusion: Our fi ndings showed that the HALP score, which comprises four hematological parameters, can be a valuable biomarker that can be used to predict in-hospital mortality.
Açıklama
Anahtar Kelimeler
Acute Pulmonary Embolism, Biomarker, HALP Score, In-hospital Mortality
Kaynak
Cor et Vasa
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
66
Sayı
3
