The importance of speckle tracking echocardiography in the early detection of left ventricular dysfunction in patients with polycystic ovary syndrome

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dc.contributor.authorDemirelli, Selami
dc.contributor.authorDe?irmenci, Hüsnü
dc.contributor.authorErmiş, Emrah
dc.contributor.authorİnci, Sinan
dc.contributor.authorNar, Gökay
dc.contributor.authorAyhan, Mehmet Emin
dc.contributor.authorFırtına, Serdar
dc.contributor.authorHamur, Hikmet
dc.contributor.authorDurmaz, Şenay Arıkan
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T08:22:18Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T08:22:18Z
dc.date.issued2015
dc.departmentTıp Fakültesi
dc.descriptionPubMed ID: 26614851
dc.description.abstractPolycystic ovary syndrome (PCOS) is characterized by hormonal and metabolic abnormalities and is thought to increase a risk for cardiovascular diseases. In this study we use speckle tracking echocardiography (STE) to evaluate left ventricular (LV) dysfunction in the early period of the disease. We enrolled 31 patients with PCOS and 32 healthy volunteers as a control group. The participants’ ages ranged between 18 and 40 years. PCOS was diagnosed according to the Rotterdam criteria. LV strain (LS) and strain rate (SR) were evaluated using apical two-chamber (2C), three-chamber (3C), and four-chamber (4C) imaging. Global LS and SR were calculated as average of three apical views. The waist-to-hip ratio, homeostasis model assessment-insulin resistance (HOMA-IR), and fasting insulin and triglyceride levels were higher in the PCOS group than in the controls (p = 0.001, p = 0.001, p = 0.001, and p = 0.005, respectively). In the PCOS group, the mitral A wave, deceleration time (DT), and isovolumetric relaxation time (IVRT) were significantly higher than in the controls (all p < 0.05). The LV global longitudinal strain (GLS) and global longitudinal SR systolic (GLSRS) were significantly lower in the PCOS patient group (both p = 0.001). There were strong negative correlations between GLS and both fasting insulin (r = -0.64) and DT (r =-0.62) (both p < 0.05). The study demonstrated that PCOS patients had decreased LV function using STE. Therefore, STE imaging appears to be useful for the early detection of subclinical LV dysfunction in patients with PCOS. © 2015 ABMSFBIH.
dc.identifier.doi10.17305/bjbms.2015.552
dc.identifier.endpage49en_US
dc.identifier.issn1512-8601
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage44en_US
dc.identifier.urihttps://dx.doi.org/10.17305/bjbms.2015.552
dc.identifier.urihttps://hdl.handle.net/20.500.12451/2526
dc.identifier.volume15en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAssociation of Basic Medical Sciences Federation of Bosnia and Herzegovina
dc.relation.ispartofBosnian Journal of Basic Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPolycystic Ovary Syndrome
dc.subjectSpeckle Tracking Echocardiography
dc.subjectSubclinical Left Ventricular Dysfunction
dc.titleThe importance of speckle tracking echocardiography in the early detection of left ventricular dysfunction in patients with polycystic ovary syndrome
dc.typeArticle

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