Use of the CHA2DS2‑VASc Score to Predict Concurrent Critical Coronary Artery Stenosis in Patients with Severe Carotid Artery Disease

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dc.contributor.authorBaran, O.
dc.contributor.authorYılmaz, Y.
dc.contributor.authorİnci, S.
dc.contributor.authorÇetinkaya, Z.
dc.contributor.authorKeleşoğlu, S.
dc.date.accessioned2025-07-11T07:38:30Z
dc.date.available2025-07-11T07:38:30Z
dc.date.issued2025
dc.departmentTıp Fakültesi
dc.description.abstractThere is a significant correlation between the severity of atherosclerosis in one arterial region and the occurrence of atherosclerotic disease in other regions. Identifying and managing vascular disease in patients with multifocal arterial disease is often complex. The CHA2DS2-VASc score encompasses several cardiovascular risk factors and was initially used to assess the risk of thromboembolism, stroke, and death in patients with atrial fibrillation. In recent years, this score has been proposed to predict the prognosis of various cardiovascular diseases. Aim: The study aimed to investigate the prevalence of concomitant coronary artery disease (CAD) and the correlation between the CHA2DS2-VASc score and CAD in patients who were scheduled for carotid stenting due to carotid artery stenosis (CAS) but had no history of CAD. Methods: A total of 452 patients were included in the study, 213 with symptomatic CAS and 239 with asymptomatic CAS. The patients were separated into two groups: those with and without. Results: One hundred forty-eight (32.7%) of 452 patients had critical CAD. Multivariate logistic regression analysis showed that a high CHA2DS2-VASc score (OR: 4.283, 95% CI: 2.903–6.321, P < 0.001) was an independent predictor of the development of CAD. Receiver operating characteristic curve (ROC) analysis showed 64.9% sensitivity and 82% specificity in detecting CAD of the CHA2DS2-VASc score at >4 cutoff [Area under ROC curve = 0.781 (95% CI: 0.724–0.838), P < 0.001]. Conclusion: When our results were analyzed, a CHA2DS2-VASc score of >4 was highly significant in predicting severe CAD.
dc.identifier.doi10.4103/njcp.njcp_759_24
dc.identifier.endpage495
dc.identifier.issn11193077
dc.identifier.issue4
dc.identifier.pmid40289005
dc.identifier.scopus105003932446
dc.identifier.startpage487
dc.identifier.urihttps://dx.doi.org/10.4103/njcp.njcp_759_24
dc.identifier.urihttps://hdl.handle.net/20.500.12451/13257
dc.identifier.volume28
dc.identifier.wosWOS:001477061000011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorİnci, S.
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCarotid Artery Stenosis
dc.subjectCHA2DS2‑VASc Score
dc.subjectCoronary Artery Disease
dc.titleUse of the CHA2DS2‑VASc Score to Predict Concurrent Critical Coronary Artery Stenosis in Patients with Severe Carotid Artery Disease
dc.typeArticle

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