Protective effect of Funalia trogii crude extract on deltamethrin-induced oxidative stress in rats

dc.authoriden_US
dc.contributor.authorMazmancı, Birgül
dc.contributor.authorMazmancı, Mehmet Ali
dc.contributor.authorÜnyayar, Ali
dc.contributor.authorÜnyayar, Serpil
dc.contributor.authorÇekiç, Fazilet Özlem
dc.contributor.authorDeğer, Ayşin Güzel
dc.contributor.authorYalın, Serap
dc.contributor.authorÇömelekoğlu, Ülkü
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-29T19:26:41Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-29T19:26:41Z
dc.date.issued2011
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractIn this study the protective effects of cold buffer extract of Funalia trogii ATCC 200800 (FtE) and vitamin E (VitE) on oxidative stress induced with deltamethrin using oral administration in rats were investigated. Deltamethrin treatment caused an increase in liver enzyme activities of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP) (p < 0.05); however, it caused a decrease in activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and glutathione reductase (GRd) when compared to control group (p < 0.05). Activities of AST, ALT, ALP enzymes and level of thiobarbituric acid reactive substances (TBARS) decreased significantly after VitE administration (p < 0.05). Both enzyme activities and TBARS levels were found similar in VitE and FtE treated rats shortly after pesticide administration (p < 0.05). In conclusion, it appears that FtE prepared in cold buffer has capability to prevent the liver damage like VitE against the toxic effect of deltamethrin. (C) 2010 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/j.foodchem.2010.10.014
dc.identifier.endpage1040en_US
dc.identifier.issn0308-8146
dc.identifier.issn1873-7072
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage1037en_US
dc.identifier.urihttps://doi.org/10.1016/j.foodchem.2010.10.014
dc.identifier.urihttps://hdl.handle.net/20.500.12451/5676
dc.identifier.volume125en_US
dc.identifier.wosWOS:000284818400031
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFood Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectFunalia Trogii
dc.subjectCold Buffer Extract
dc.subjectDeltamethrin
dc.subjectAntioxidant Enzymes
dc.subjectLiver Enzymes
dc.titleProtective effect of Funalia trogii crude extract on deltamethrin-induced oxidative stress in rats
dc.typeArticle

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