Evaluating the efficacy and benefits of vNOTES for ovarian cystectomy: a systematic review and meta-analysis

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dc.authorid0000-0003-1325-6294
dc.contributor.authorKaya, Cihan
dc.contributor.authorAktoz, Fatih
dc.contributor.authorGüneş, Ali Can
dc.contributor.authorTercan, Can
dc.contributor.authorSaçıntı, Koray Görkem
dc.contributor.authorYassa, Murat
dc.contributor.authorAlAli, Hussein
dc.date.accessioned2025-09-17T13:02:06Z
dc.date.available2025-09-17T13:02:06Z
dc.date.issued2025
dc.departmentTıp Fakültesi
dc.description.abstractThis meta-analysis aims to evaluate the effectiveness and overall outcomes of vNOTES in ovarian cystectomy compared to conventional laparoscopy (CL). Study design: A systematic review and meta-analysis were conducted by searching PubMed/MEDLINE, EBSCO, Cochrane, and Embase databases for studies comparing vNOTES and laparoscopy for ovarian cystectomy. A comprehensive literature search was performed to identify relevant publications up to June 21, 2024. The search strategy utilized a combination of Medical Subject Headings (MeSH) terms and relevant keywords. Eligible studies included randomized controlled trials, cohort studies, and case-control studies, while case reports and studies lacking a direct comparison were excluded. Two independent reviewers assessed study eligibility and performed Risk of Bias evaluation. Quantitative synthesis was performed using meta-analysis techniques. The protocol was registered in the PROSPERO database (CRD42024560612). Results: Six studies reported operative times, with vNOTES showing a significantly shorter duration compared to CL (mean difference [MD]: −13.05 min, 95 % confidence interval [CI]: −19.04 to −7.07, I2 = 67 %). Five studies demonstrated that vNOTES was associated with shorter hospital stays (MD: −0.43 days, 95 % CI: −0.74 to −0.12, I2 = 90 %). Pain scores were also significantly lower in vNOTES patients (3 studies, MD: −1.25, 95 % CI: −1.49 to −1.01, I2 = 43 %). However, no significant differences were observed between the groups regarding hemoglobin drop, blood loss, or conversion rates. Conclusion: This systematic review and meta-analysis highlight the advantages of vNOTES ovarian cystectomy, including reduced operative times, faster recovery, lower postoperative pain, and shorter hospital stays. These findings support the wider adoption of vNOTES as an effective alternative to conventional laparoscopy for ovarian cystectomy, offering potential benefits for both patients and surgical efficiency.
dc.identifier.doi10.1016/j.ejogrb.2025.114596
dc.identifier.issn03012115
dc.identifier.pmid40712463
dc.identifier.scopus2-s2.0-105011264475
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2025.114596
dc.identifier.urihttps://hdl.handle.net/20.500.12451/14444
dc.identifier.volume313
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakScopus
dc.institutionauthorSaçıntı, Koray Görkem
dc.language.isoen
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofEuropean Journal of Obstetrics and Gynecology and Reproductive Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNatural Orifice Endoscopic Surgery
dc.subjectvNOTES
dc.subjectLaparoscopy
dc.subjectOperation Time
dc.subjectOvarian Cystectomy
dc.subjectMinimally Invasive Surgery
dc.titleEvaluating the efficacy and benefits of vNOTES for ovarian cystectomy: a systematic review and meta-analysis
dc.typeOther

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