In vitro biocompatibility of plasma-aided surface-modified 316L stainless steel for intracoronary stents

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dc.authoridBayram, Cem -- 0000-0001-8717-4668;
dc.contributor.authorBayram, Cem
dc.contributor.authorMızrak, Alpay Koray
dc.contributor.authorAktürk, Selçuk
dc.contributor.authorKurşaklıoğlu, Hürkan
dc.contributor.authorİyisoy, Atila
dc.contributor.authorİfran, Ahmet
dc.contributor.authorDenkbaş, Emir Baki
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-29T19:26:50Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-29T19:26:50Z
dc.date.issued2010
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstract316L-type stainless steel is a raw material mostly used for manufacturing metallic coronary stents. The purpose of this study was to examine the chemical, wettability, cytotoxic and haemocompatibility properties of 316L stainless steel stents which were modified by plasma polymerization. Six different polymeric compounds, polyethylene glycol, 2-hydroxyethyl methacrylate, ethylenediamine, acrylic acid, hexamethyldisilane and hexamethyldisiloxane, were used in a radio frequency glow discharge plasma polymerization system. As a model antiproliferative drug, mitomycin-C was chosen for covalent coupling onto the stent surface. Modified SS 316L stents were characterized by water contact angle measurements (goniometer) and x-ray photoelectron spectroscopy. C1s binding energies showed a good correlation with the literature. Haemocompatibility tests of coated SS 316L stents showed significant latency (t-test, p < 0.05) with respect to SS 316L and control groups in each test.
dc.description.sponsorshipScientific and Technological Research Council of Turkey; Health Sciences Research Group (SBAG) [106S182]
dc.description.sponsorshipThis work was funded by The Scientific and Technological Research Council of Turkey, Health Sciences Research Group (SBAG) project number 106S182. Additionally, the stents used in this study were kindly gifted by Alvimedica Medical Inc., Turkey.
dc.identifier.doi10.1088/1748-6041/5/5/055007
dc.identifier.issn1748-6041
dc.identifier.issue5en_US
dc.identifier.pmid20844318
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1088/1748-6041/5/5/055007
dc.identifier.urihttps://hdl.handle.net/20.500.12451/5720
dc.identifier.volume5en_US
dc.identifier.wosWOS:000282277300025
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherIOP Publishing LTD
dc.relation.ispartofBiomedical Materials
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleIn vitro biocompatibility of plasma-aided surface-modified 316L stainless steel for intracoronary stents
dc.typeArticle

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