A novel breath molecule sensing system based on deep neural network employing multiple-line direct absorption spectroscopy

dc.contributor.authorBayraklı, İsmail
dc.contributor.authorEken, Enes
dc.date.accessioned2023-02-23T12:57:30Z
dc.date.available2023-02-23T12:57:30Z
dc.date.issued2023
dc.departmentMühendislik Fakültesi
dc.description.abstractA novel ppb-level biomedical sensor is developed to analyze breath samples for continuous monitoring of diseases. The setup is very compact, consisting of a distributed feedback quantum cascade laser (DFB-QCL) and a single-pass absorption cell. To make the sensor more compact and functional, a deep neural network (DNN) model is utilized for predicting gas concentrations. In order to evaluate the performance of the sensor, N2O is used as the target molecule. A minimum detection limit of 500 ppb is achieved in a single-pass absorption cell configuration. The model is trained on multiple N2O/CO2 absorption lines (instead of an isolated line) with concentrations between 0 to 500 ppm generated using the HITRAN database. The trained model is tested on measured spectra and compared to a non-linear least squares fitting algorithm. The coefficients of determination (R2) were found to be 0.997 and 0.981 for the predictions of N2O concentrations in the N2O/N2 gas mixture and the breath air, respectively. The accuracies of 2.5% and 2.9% were achieved by the sensor for both cases.
dc.identifier.doi10.1016/j.optlastec.2022.108918
dc.identifier.issn0030-3992
dc.identifier.scopusqualityQ1
dc.identifier.urihttps:/dx.doi.org/10.1016/j.optlastec.2022.108918
dc.identifier.urihttps://hdl.handle.net/20.500.12451/10281
dc.identifier.volume158en_US
dc.identifier.wosWOS:000904474500002
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofOptics and Laser Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectSensor
dc.subjectLaser Spectroscopy
dc.subjectBreath Air Analysis
dc.subjectDeep Neural Networks
dc.subjectMachine Learning
dc.subjectLong-short term Memory
dc.titleA novel breath molecule sensing system based on deep neural network employing multiple-line direct absorption spectroscopy
dc.typeArticle

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