A novel breath molecule sensing system based on deep neural network employing multiple-line direct absorption spectroscopy
Yükleniyor...
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ltd
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Özet
A novel ppb-level biomedical sensor is developed to analyze breath samples for continuous monitoring of diseases. The setup is very compact, consisting of a distributed feedback quantum cascade laser (DFB-QCL) and a single-pass absorption cell. To make the sensor more compact and functional, a deep neural network (DNN) model is utilized for predicting gas concentrations. In order to evaluate the performance of the sensor, N2O is used as the target molecule. A minimum detection limit of 500 ppb is achieved in a single-pass absorption cell configuration. The model is trained on multiple N2O/CO2 absorption lines (instead of an isolated line) with concentrations between 0 to 500 ppm generated using the HITRAN database. The trained model is tested on measured spectra and compared to a non-linear least squares fitting algorithm. The coefficients of determination (R2) were found to be 0.997 and 0.981 for the predictions of N2O concentrations in the N2O/N2 gas mixture and the breath air, respectively. The accuracies of 2.5% and 2.9% were achieved by the sensor for both cases.
Açıklama
Anahtar Kelimeler
Sensor, Laser Spectroscopy, Breath Air Analysis, Deep Neural Networks, Machine Learning, Long-short term Memory
Kaynak
Optics and Laser Technology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
158