Distribution of neuroendocrine cells in the small and large intestines of the mole-rats (Spalax leucodon)
| dc.contributor.author | Bayrakdar, Ali | |
| dc.contributor.author | Yaman, Mine | |
| dc.contributor.author | İlgün, Ramazan | |
| dc.date.accessioned | 2019-07-10T12:21:54Z | |
| dc.date.available | 2019-07-10T12:21:54Z | |
| dc.date.issued | 2015 | |
| dc.department | Veteriner Fakültesi | |
| dc.description.abstract | In this research, we aimed to determine the regional distribution and relative frequency of immunoreactive (IR) endocrine cells of ghrelin, glucagon, somatostatin–14 (SOM–14), neuropeptide Y (NPY), calcitonin-gene-related peptide (CGRP), insulin and galanin in small and large intestines of mole-rats (Spalax leucodon) by using immunohistochemical staining methods. For this purpose, small and large intestine regions of six adult mole-rats were used as material. In the small and large intestines of mole-rats (S. leucodon), ghrelin, glucagon, SOM–14, NPY and CGRP were identified at various frequencies, but insulin and galanin were not detected in this study. Ghrelin-IR cells were only observed in the small intestine. In addition, the existence of positive staining in the cells was decreased while passing from duodenum to ileum. Glucagon-IR cells were mainly detected in the small intestine regions and colon. SOM–14-IR cells were detected throughout the small intestines with a lesser frequency. NPY-IR cells were also detected in the small and large intestines at various frequencies but not in cecum and rectum. CGRP-IR cells were scarce in duodenum and jejunum, but their numbers increased from ileum to colon. In conclusion, the present study revealed the existence and distributions of neuropeptide-secreting endocrine cells in small and large intestines of mole-rats (S. leucodon). | |
| dc.identifier.doi | 10.1080/19768354.2015.1074105 | |
| dc.identifier.endpage | 294 | en_US |
| dc.identifier.issn | 1976-8354 | |
| dc.identifier.issue | 5 | en_US |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | 289 | en_US |
| dc.identifier.uri | https:/dx.doi.org/10.1080/19768354.2015.1074105 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/2097 | |
| dc.identifier.volume | 19 | en_US |
| dc.identifier.wosquality | N/A | |
| dc.indekslendigikaynak | Web of Science | |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | Taylor and Francis Ltd. | |
| dc.relation.ispartof | Animal Cells and Systems | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Mole-Rats (Spalax Leucodon) | |
| dc.subject | Gastrointestinal Tract | |
| dc.subject | İmmunohistochemistry | |
| dc.title | Distribution of neuroendocrine cells in the small and large intestines of the mole-rats (Spalax leucodon) | |
| dc.type | Article |
