Real time monitoring and label free creatinine detection with artificial receptors

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dc.contributor.authorTopçu, Aykut Arif
dc.contributor.authorÖzgür, Erdo?an
dc.contributor.authorYılmaz, Fatma
dc.contributor.authorBereli, Nilay
dc.contributor.authorDenizli, Adil
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:16:20Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:16:20Z
dc.date.issued2019
dc.departmentFen-Edebiyat Fakültesi
dc.description.abstractMolecular imprinting technique is used to design artificial creatinine receptor on the gold surface of surface plasmon resonance (SPR) chip using N-methacryloyl-(L)-histidine methyl ester (MAH), as a functional monomer. Surface characterization of SPR sensor chip is performed with atomic force microscope (AFM), ellipsometry and contact angle measurements. Creatinine imprinted SPR sensor is characterized with a linear range between 1 and 100 mM and limit of detection (LOD) and limit of quantification (LOQ) of creatinine are found 57 mu M and 190 mu M, respectively. N-hydroxysuccinimide (NHS) and creatine molecules are selected to examine the selectivity of creatinine imprinted SPR sensor. Reusability studies of SPR sensor is determined in urine mimic samples.
dc.description.sponsorshipRepublic of Turkey, Ministry of Science, Industry and Technology [0505_TGSD.2015_2]
dc.description.sponsorshipThis study was funded and supported by Republic of Turkey, Ministry of Science, Industry and Technology (Grand No. 0505_TGSD.2015_2).
dc.identifier.doi10.1016/j.mseb.2019.04.018
dc.identifier.endpage11en_US
dc.identifier.issn0921-5107
dc.identifier.issn1873-4944
dc.identifier.scopusqualityQ1
dc.identifier.startpage6en_US
dc.identifier.urihttps://doi.org/10.1016/j.mseb.2019.04.018
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4576
dc.identifier.volume244en_US
dc.identifier.wosWOS:000471359400002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherELSEVIER SCIENCE BV
dc.relation.ispartofMATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCreatinine
dc.subjectSurface Plasmon Resonance
dc.subjectMolecular Imprinting
dc.subjectArtificial Receptor
dc.titleReal time monitoring and label free creatinine detection with artificial receptors
dc.typeArticle

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