Cascaded contraction-expansion channels for bacteria separation from RBCs using viscoelastic microfluidics
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Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
Attribution-NonCommercial-NoDerivs 3.0 United States
info:eu-repo/semantics/embargoedAccess
info:eu-repo/semantics/embargoedAccess
Özet
Implementation of viscoelasticity-based particle migration techniques has attracted significant interest thanks to its simplicity to achieve particle separation and enrichment at high sensitivity and accuracy for the last decade. Many methods have previously been developed for particle focusing and separation, but they all require long fluidic channels to enable the desired elastic force on particles. Here, a cascade contraction-expansion microfluidic system with a much shorter channel length is presented. Experimental results show that this system achieved continuous, sheathless particle separation in a viscoelastic fluid, and Enterococcus faecalis was successfully separated from red blood cells (RBCs). Thanks to its small size, the system provides extra advantage for its integration into small chips. (c) 2021 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Bacteria, Focusing, RBCs, Separation, Viscoelastic
Kaynak
Journal of Chromatography A
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
1652
Sayı
-