Cascaded contraction-expansion channels for bacteria separation from RBCs using viscoelastic microfluidics

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Küçük Resim

Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier

Erişim Hakkı

Attribution-NonCommercial-NoDerivs 3.0 United States
info:eu-repo/semantics/embargoedAccess

Özet

Implementation of viscoelasticity-based particle migration techniques has attracted significant interest thanks to its simplicity to achieve particle separation and enrichment at high sensitivity and accuracy for the last decade. Many methods have previously been developed for particle focusing and separation, but they all require long fluidic channels to enable the desired elastic force on particles. Here, a cascade contraction-expansion microfluidic system with a much shorter channel length is presented. Experimental results show that this system achieved continuous, sheathless particle separation in a viscoelastic fluid, and Enterococcus faecalis was successfully separated from red blood cells (RBCs). Thanks to its small size, the system provides extra advantage for its integration into small chips. (c) 2021 Elsevier B.V. All rights reserved.

Açıklama

Anahtar Kelimeler

Bacteria, Focusing, RBCs, Separation, Viscoelastic

Kaynak

Journal of Chromatography A

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

1652

Sayı

-

Künye