Poly(vinyl chloride) Derived Food Packaging Applications with Antioxidative and Anticancer Properties

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dc.contributor.authorHazer, Baki
dc.contributor.authorKarahaliloğlu, Zeynep
dc.contributor.authorAshby, Richard D.
dc.date.accessioned2023-10-04T06:21:51Z
dc.date.available2023-10-04T06:21:51Z
dc.date.issued2023
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractNovel poly(vinyl chloride) (PVC) polymer derivatives based on the natural antioxidants vanillic acid, cinnamic acid, coumaric acid, caffeic acid, and naringin were prepared and characterized for their chemical structures, molecular weights, thermal and mechanical properties, and antioxidant characteristics toward linseed oil. Oxidation delay times (induction periods) were prolonged from 1 to 6 days beyond the pristine PVC, with the naringin-based derivative being the most effective. Biological activities of the PVC derivatives were determined and showed the substituted PVC polymers effectively inhibited the formation of reactive oxygen species (ROS) in the MCF-7 cell line according to the following sequence: cinnamic acid ? caffeic acid ? vanillic acid = naringin ? coumaric acid, with only a minimal effect on healthy L929 cells. These results indicate that the derivatives produced in this study have potential applications as active packaging materials for food and as antibacterial/anticancer biomaterials in areas such as tissue engineering.
dc.identifier.doi10.1021/acsfoodscitech.3c00021
dc.identifier.endpage771en_US
dc.identifier.issn2692-1944
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2
dc.identifier.startpage761en_US
dc.identifier.urihttps:/dx.doi.org10.1021/acsfoodscitech.3c00021
dc.identifier.urihttps://hdl.handle.net/20.500.12451/11062
dc.identifier.volume3en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmerican Chemical Society
dc.relation.ispartofACS Food Science and Technology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectActive Food Packaging Material
dc.subjectAntibacterial
dc.subjectAnticancer
dc.subjectAntioxidant
dc.subjectNatural Substances
dc.subjectPoly(vinyl chloride) Derivatives
dc.titlePoly(vinyl chloride) Derived Food Packaging Applications with Antioxidative and Anticancer Properties
dc.typeArticle

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